Baby Neena, Varghese Prasanth, Kunnathuparambil Sabu George, Kuriakose Aneesh Mangalasseril
Department of Neurology, Jubilee Mission Medical College Hospital and Research Institute, Thrissur, Kerala, India.
Department of Radiology, Jubilee Mission Medical College Hospital and Research Institute, Thrissur, Kerala, India.
Neurol India. 2020 Sep-Oct;68(5):1214-1216. doi: 10.4103/0028-3886.299159.
Hypophysitis occurs predominantly in women, usually during pregnancy or postpartum period. Hypophysitis involving the anterior pituitary often presents with adrenal insufficiency.
DESIGN/METHODS: We describe a 43-year-old woman who presented with recurrent episodes of alteration of sensorium due to hyponatremia. She had a 3-month history of amenorrhea and on evaluation had evidence of pan-hypopituitarism. The magnetic resonance images of the brain showed mild pituitary enlargement and thickened pituitary stalk with homogenous contrast enhancement indicating hypophysitis. She was treated with oral steroids and thyroxine supplements. She remained asymptomatic at 15-month follow-up on low-dose oral steroids and thyroxine supplements.
Hypopituitarism due to hypophysitis resulted in recurrent episodes of hyponatremia in our patient.
Our case highlights the importance of a systematic search for the etiology for hyponatremic encephalopathy.
垂体炎主要发生于女性，通常在妊娠或产后期间。累及垂体前叶的垂体炎常表现为肾上腺功能不全。
设计/方法：我们描述了一名43岁女性，因低钠血症反复出现意识改变发作。她有3个月闭经病史，经评估有全垂体功能减退的证据。脑部磁共振成像显示垂体轻度增大，垂体柄增粗，均匀强化，提示垂体炎。她接受了口服类固醇和甲状腺素补充治疗。在低剂量口服类固醇和甲状腺素补充治疗下，15个月随访时她仍无症状。
垂体炎导致的垂体功能减退在我们的患者中引起了低钠血症的反复发 作。
我们的病例强调了系统寻找低钠性脑病病因的重要性。
