Fisher Raymond, Vandehei Anthony, Haller Charles, Boster Joshua, Shipley Brian, Kaatz Christopher, Harris Jaclyn, Shin Satoshi R, Townsend Lisa, Rouse Jessica, Davis Sarah, Aden James, Thomas Dustin
Cardiology, Brooke Army Medical Center, Fort Sam Houston, USA.
Internal Medicine, Brooke Army Medical Center, Fort Sam Houston, USA.
Cureus. 2020 Sep 21;12(9):e10579. doi: 10.7759/cureus.10579.
Background Coronary artery calcium (CAC) scoring based on gated non-contrast cardiac computed tomography (CT) is a validated risk marker of major adverse cardiovascular events (MACE). Reporting of CAC on non-gated CT chest (NGCT) scans and the impact on medical therapy is not well studied. Methods A retrospective cohort of 5,043 NGCT scans was reviewed for the presence of CAC. The radiology report was reviewed to determine whether CAC was mentioned in either the body of the report or the final impression. Electronic medical records (EMR) were abstracted for baseline demographics, cardiovascular (CV) risk factors, lipid-lowering agents, and aspirin (ASA) prior to and after NGCT. Results CAC was present in 63.0% of NGCT scans. Of these scans, CAC was mentioned in the body of the report in 81.6% of studies. Conversely, CAC was mentioned in the final impressions in only 15.1% of these scans. Amongst patients with CAC, initiation of a statin in treatment-naive patients was more common when CAC was mentioned in the final impression versus the body only (12.3% vs. 4.9%, p=0.001) despite the fact that baseline utilization of statins in this cohort was higher (71.1% vs. 64.1%, p=0.005). Initiation of a statin in treatment-naive patients had a trend towards significance when CAC was mentioned in the body of the report versus not reported (4.9% vs. 2.62%, p=0.142). Reporting of CAC in the final impression significantly increased the initiation of ASA in treatment-naive patients (9.52% vs. 4.33%, p=0.033). Reporting of CAC in either the final impression or the body of the report did not affect the initiation of non-statin lipid-lowering therapies in patients with CAC. Conclusion The inclusion of CAC in the final impression of NGCT radiology reports positively impacts the appropriate initiation of statin and aspirin therapy in treatment-naive patients. Universal adherence to a standardized reporting system for the presence of CAC on NGCT should be considered to improve the initiation of guideline-directed medical therapy.
基于门控非增强心脏计算机断层扫描(CT)的冠状动脉钙化(CAC)评分是主要不良心血管事件(MACE)的有效风险标志物。非门控胸部CT(NGCT)扫描中CAC的报告情况及其对药物治疗的影响尚未得到充分研究。方法:对5043例NGCT扫描的回顾性队列进行了CAC存在情况的评估。查阅放射学报告以确定报告正文或最终印象中是否提及了CAC。提取电子病历(EMR)以获取NGCT检查前后的基线人口统计学、心血管(CV)危险因素、降脂药物和阿司匹林(ASA)使用情况。结果:63.0%的NGCT扫描存在CAC。在这些扫描中,81.6%的研究在报告正文中提到了CAC。相反,只有15.1%的扫描在最终印象中提到了CAC。在患有CAC的患者中,与仅在报告正文中提及CAC相比,当在最终印象中提及CAC时,初治患者开始使用他汀类药物更为常见(12.3%对4.9%,p=0.001),尽管该队列中他汀类药物的基线使用率较高(71.1%对64.1%,p=0.005)。当在报告正文中提及CAC与未提及相比,初治患者开始使用他汀类药物有显著趋势(4.9%对2.62%,p=0.142)。在最终印象中报告CAC显著增加了初治患者ASA的使用(9.52%对4.33%,p=0.033)。在最终印象或报告正文中报告CAC均未影响患有CAC患者非他汀类降脂治疗的开始。结论:在NGCT放射学报告的最终印象中纳入CAC对初治患者他汀类药物和阿司匹林治疗的合理开始有积极影响。应考虑普遍遵循关于NGCT上CAC存在情况的标准化报告系统,以改善指南指导的药物治疗的开始。