糖尿病患者含IgA循环免疫复合物中IgA1和IgA2亚类分布的分析
Analysis of IgA1 and IgA2 subclass distribution in IgA- containing circulating immune complexes in patients with diabetes mellitus.
作者信息
Triolo G, Giardina E, Seddio G, Terrizzi C
机构信息
Istituto di Clinica Medica, University of Palermo, Italy.
出版信息
Boll Ist Sieroter Milan. 1987;66(2):116-9.
PMID:3311077
Abstract
Immune complexes (IC) containing IgA1 and IgA2 have been detected in diabetes mellitus. In particular IgA1 and IgA2-IC are equally distributed in type 2 diabetes. On the other hands IgA1-IC are prevailingly found in type 1 diabetes mellitus. IgA2-IC (immune complexes of "mucosal" origin?) seen to be of relevance in the pathogenesis of diabetic microangiopathy.
摘要
在糖尿病患者中已检测到含有IgA1和IgA2的免疫复合物（IC）。特别是IgA1和IgA2免疫复合物在2型糖尿病中分布均匀。另一方面，IgA1免疫复合物在1型糖尿病中更为常见。IgA2免疫复合物（“黏膜”来源的免疫复合物？）似乎与糖尿病微血管病变的发病机制有关。
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