Khan Fahad, Khan Saad, Masud Sarwat, Masud Nazish
Department of Medicine, Khyber Teaching Hospital, Khyber Medical University, Peshawar, Khyber Pakhtunkhwa, Pakistan.
Emergency Department, Agha Khan University, Karachi, Sindh, Pakistan.
J Family Med Prim Care. 2020 Aug 25;9(8):4418-4420. doi: 10.4103/jfmpc.jfmpc_541_20. eCollection 2020 Aug.
Glioblastoma multiforme (GBM) is a high-grade tumor of the brain that arises from the supporting cells of neurons (astrocytes and oligodendrocytes) within the brain. GBM is a rare occurrence in children but fatal; hence, timely diagnosis is crucial to the prognosis of the patients. While GBM can present with several signs and symptoms, headaches and vomiting and headaches relieved by vomiting are common presenting complaints. Strabismus is an uncommon sign of GBM. Here, we discuss an 18-year-old girl diagnosed with GBM who presented with strabismus and was initially misdiagnosed as a squint and revise some of the literature already present on Glioblastoma multiforme.
多形性胶质母细胞瘤(GBM)是一种发生于脑内神经元支持细胞(星形胶质细胞和少突胶质细胞)的高级别脑肿瘤。GBM在儿童中较为罕见但致命,因此,及时诊断对患者的预后至关重要。虽然GBM可出现多种体征和症状,但头痛、呕吐以及呕吐后头痛缓解是常见的就诊主诉。斜视是GBM的一种罕见体征。在此,我们讨论一名18岁被诊断为GBM的女孩,她以斜视就诊,最初被误诊为斜视,并对已有的一些关于多形性胶质母细胞瘤的文献进行修订。