Instituto de Salud y Medio Ambiente, La Paz, Bolivia.
Universidad Amazónica de Pando, Pando, Bolivia.
Rev Soc Bras Med Trop. 2020 Oct 21;53:e20190421. doi: 10.1590/0037-8682-0421-2019. eCollection 2020.
In Bolivia, before 1982 there were no records of visceral leishmaniasis (VL) cases that would allow us to review and describe the temporospatial occurrence of VL by ecoregions in provinces and departments of Bolivia to evaluate its impact on public health, risk of outbreaks, or dispersion.
This update on VL in Bolivia is based on research, reviews, and retrospective literature analyses of online data and libraries and institutional reports, from 1939 to the present.
In Bolivia, 56 cases of VL have been reported. Until 2014, only three endemic departments had been identified (La Paz, Santa Cruz, and Tarija). Since then, further cases have been recorded in Pando, Cochabamba, and Beni, and in Chuquisaca in 2015. In Yungas, a VL focus was confirmed by isolating and comparing parasites from human and dog cases, and from the Lu. longipalpis vector. VL cases from seven departments, involving 12 different ecoregions were located within the Amazon and Plata basins.
We confirmed that dogs are its primary reservoir, and Lutzomyia longipalpis is its main vector (currently dispersed in six departments). The primary vectors in areas where Lutzomyia longipalpis is absent are Migonemyia migonei and Lutzomyia cruzi.
在 1982 年以前,玻利维亚没有内脏利什曼病 (VL) 的记录,因此我们无法对玻利维亚各省和地区的 VL 进行时间和空间上的回顾和描述,以评估其对公共卫生、爆发风险或传播的影响。
本研究基于对玻利维亚内脏利什曼病的研究、综述和对在线数据、图书馆和机构报告的回顾性文献分析,时间跨度为 1939 年至现在。
在玻利维亚,共报告了 56 例内脏利什曼病。直到 2014 年,仅发现三个地方性部门(拉巴斯、圣克鲁斯和塔里哈)存在 VL。此后,在潘多、科恰班巴和贝尼,以及在 2015 年的丘基萨卡省也有病例报告。在 Yungas,通过分离和比较来自人类和犬病例以及 Lu. longipalpis 媒介的寄生虫,证实了一个 VL 焦点。七个部门的 VL 病例涉及 12 个不同的生态区,位于亚马逊和拉普拉塔盆地内。
我们证实狗是其主要宿主,Lutzomyia longipalpis 是其主要媒介(目前在六个部门中传播)。在没有 Lutzomyia longipalpis 的地区,主要媒介是 Migonemyia migonei 和 Lutzomyia cruzi。