Department of Urology, Humanitas Mater Domini, Via Gerenzano 2, 21053, Varese, Castellanza, Italy.
Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090, Milan, Pieve Emanuele, Italy.
World J Urol. 2021 Jul;39(7):2475-2481. doi: 10.1007/s00345-020-03500-9. Epub 2020 Oct 28.
Urinary continence (UC) represents the main non-oncological goal in patients undergoing robotic-assisted radical prostatectomy (RARP). To evaluate the efficacy in early UC achievement, we described a new sling technique using the retrotrigonal muscular layer (TZ sling) combined with total anatomical reconstruction (TAR).
We prospectively enrolled 407 consecutive prostate cancer (PC) patients undergoing RARP between May 2017 and January 2020. The first 250 patients underwent only TAR, while the following 157 patients TAR + TZ sling, by isolating and anchoring the retrotrigonal muscular layer to the pubic bone with 2 bilateral sutures. We defined UC as ≤ 1 pad/die, which was assessed after catheter removal at 1, 4 and 12wk using the International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF) score. Sling-related operative time and post-operative complications were analyzed.
In the TAR group, the UC rates at the 1, 4 and 12wk were 58%, 66% and 86%; in the TAR + TZ sling group 72%, 76% and 88%, respectively. A statistically significant difference was observed in the two groups at 1wk (p = 0.0049) and 4wk (p = 0.035) favoring the TZ sling surgical strategy. This difference in UC rates was lost at 12wk (p ≥ 0.05). No statistically significant differences in operative time, acute urinary retentions and other complication rates were observed between the two groups (p = NS).
We have described a new, safe, feasible modification of RARP using a sling with the retrotrigonal muscular layer associated with TAR. We have demonstrated a statistically significant improvement in early UC rate in patients who are undergoing TAR and TZ sling compared to undergoing only TAR.
尿控(UC)是接受机器人辅助根治性前列腺切除术(RARP)患者的主要非肿瘤学目标。为了评估早期 UC 实现的疗效,我们描述了一种使用后三角肌层(TZ 吊带)结合完全解剖重建(TAR)的新吊带技术。
我们前瞻性纳入了 2017 年 5 月至 2020 年 1 月期间接受 RARP 的 407 例连续前列腺癌(PC)患者。前 250 例仅接受 TAR,随后 157 例接受 TAR+TZ 吊带,通过将后三角肌层隔离并固定在耻骨上,使用 2 对双侧缝线。我们将 UC 定义为≤1 个尿垫/天,使用国际尿失禁咨询问卷-短表(ICIQ-SF)评分在拔除导尿管后 1、4 和 12 周评估。分析吊带相关手术时间和术后并发症。
在 TAR 组中,UC 率在 1、4 和 12 周时分别为 58%、66%和 86%;在 TAR+TZ 吊带组中分别为 72%、76%和 88%。两组在 1 周(p=0.0049)和 4 周(p=0.035)时差异有统计学意义,TZ 吊带手术策略更有利。在 12 周时,UC 率的差异消失(p≥0.05)。两组在手术时间、急性尿潴留和其他并发症发生率方面无统计学差异(p=NS)。
我们描述了一种使用后三角肌层吊带结合 TAR 的新型、安全、可行的 RARP 改良方法。我们已经证明,与仅接受 TAR 的患者相比,接受 TAR 和 TZ 吊带的患者在早期 UC 率方面有统计学意义的改善。