Velasco-Velásquez Stefany, Celis-Giraldo Daniel, Botero Hincapié Andrea, Alejandro Hincapie Erira Diego, Sofia Cordero López Sara, Marulanda Orozco Nathalia, Enrique Gómez-Marín Jorge
Group of Studies on Molecular Parasitology (GEPAMOL), Center of Biomedical Research, Faculty of Health Sciences, Universidad Del Quindío, Armenia, Colombia.
Ophthalmic Epidemiol. 2021 Jun;28(3):258-264. doi: 10.1080/09286586.2020.1839509. Epub 2020 Oct 28.
To identify the sociodemographic, clinical, and environmental factors associated with recurrences in ocular toxoplasmosis (OT).
Retrospective analysis of clinical records of patients who consulted in the Health Centre at Universidad del Quindío between 2004 and 2017. Patients with retinochoroiditis due to infection and follow up >12 months were included. Comparisons were made with a recurrence index adjusted for months of follow up. For the statistical analysis, the Kruskal-Wallis test and analysis of variance (ANOVA) tests were performed in Epi Info 7.2 and SPSS 14.0. A statistical significance is shown if p ≤ 0.05.
A total of 58 patients were included, with median age of 28 years (range 1-61) and 55.1% were women. The median of recurrences was 1.4 (range 0.6-16.6). High recurrence index was present in 43.1% of the patients. A higher size of lesions was observed in low socioeconomic groups ( = .016) and patients with congenital infection had more bilateral compromise ( = .002). Intake of boiled water was related to a lower recurrence index ( = .04).
Low socioeconomic level was associated with bigger lesions and congenital infection was related with higher frequency of bilateral OT. Finally, intake of boiled water is related to a lower recurrence index of OT.
确定与眼部弓形虫病（OT）复发相关的社会人口统计学、临床和环境因素。
对2004年至2017年间在金迪奥大学健康中心就诊的患者临床记录进行回顾性分析。纳入因感染导致视网膜脉络膜炎且随访时间>12个月的患者。通过对随访月数进行调整的复发指数进行比较。对于统计分析，在Epi Info 7.2和SPSS 14.0中进行Kruskalkal-W检验和方差分析（ANOVA）检验。如果p≤0.05，则显示具有统计学意义。
共纳入58例患者，中位年龄为28岁（范围1 - 61岁），女性占55.1%。复发中位数为1.4（范围0.6 - 16.6）。43.1%的患者复发指数较高。在社会经济地位较低的群体中观察到更大的病变尺寸（p = 0.016），先天性感染的患者双侧受累更多（p = 0.002）。饮用开水与较低的复发指数相关（p = 0.04）。
社会经济水平低与更大的病变相关，先天性感染与双侧OT的更高频率相关。最后，饮用开水与OT的较低复发指数相关。
