Department of Plastic, Reconstructive, Aesthetic and Hand Surgery, University Hospital Basel, Basel, Switzerland.
Institute of Pathology, University Hospital and University of Basel, Basel, Switzerland.
J Hand Surg Asian Pac Vol. 2020 Dec;25(4):513-514. doi: 10.1142/S2424835520720194.
We present the case of a severe and long-standing Dupuytren's contracture where intraoperatively an ossified nodule was encountered within the diseased tissue. Histologically palmar fibromatosis in contact with cartilaginous tissue with central ossification could be confirmed, compatible with metaplasia. Our finding suggests that metaplastic activity inherent to longstanding, severely diseased Dupuytren's tissue can lead to heterotopic ossification.
我们报告了一例严重且长期存在的掌腱膜挛缩症病例,术中在病变组织中遇到了一个骨化结节。组织学上可以证实与软骨组织接触的掌侧纤维瘤病伴有中央骨化,符合化生。我们的发现表明,长期严重患病的掌腱膜挛缩组织固有的化生活性可导致异位骨化。