支架治疗后即刻经皮冠状动脉介入治疗的血流比和血流分数比的比较。
Comparison of Optical Flow Ratio and Fractional Flow Ratio in Stent-Treated Arteries Immediately After Percutaneous Coronary Intervention.
机构信息
Department of Cardiovascular Medicine, Wakayama Medical University.
Biomedical Instrument Institute, School of Biomedical Engineering, Shanghai Jiao Tong University.
出版信息
Circ J. 2020 Nov 25;84(12):2253-2258. doi: 10.1253/circj.CJ-20-0661. Epub 2020 Oct 29.
BACKGROUND
Optical flow ratio (OFR) is a recently developed method for functional assessment of coronary artery disease based on computational fluid dynamics of vascular anatomical data from intravascular optical coherence tomography (OCT). The purpose of this study was to investigate the relationship between OFR and fractional flow reserve (FFR) in stent-treated arteries immediately after percutaneous coronary intervention (PCI).
METHODS AND RESULTS
The OFR and FFR were measured in 103 coronary arteries immediately after successful PCI with a stent. An increase in the OFR and FFR values within the stent was defined as in-stent ∆OFR and ∆FFR, respectively. The values of FFR and OFR were 0.89±0.06 and 0.90±0.06, respectively. OFR was highly correlated with FFR (r=0.84, P<0.001). OFR showed a good agreement with FFR, presenting small values of mean difference and root-mean-squared deviation (FFR-OFR: -0.01±0.04). In-stent ∆OFR showed a moderate correlation (r=0.69, P<0.001) and good agreement (in-stent ∆FFR - in-stent ∆OFR: 0.00±0.02) with in-stent ∆FFR.
CONCLUSIONS
OFR showed a high correlation and good agreement with FFR in stent-treated arteries immediately after PCI.
背景
光学血流比（OFR）是一种基于血管解剖数据的计算流体动力学的新方法，用于评估冠状动脉疾病，这些数据来自血管内光学相干断层扫描（OCT）。本研究旨在探讨经皮冠状动脉介入治疗（PCI）后即刻支架治疗动脉中 OFR 与血流储备分数（FFR）之间的关系。
方法和结果
在成功进行 PCI 放置支架后，对 103 个冠状动脉的 OFR 和 FFR 进行了测量。支架内的 OFR 和 FFR 值增加定义为支架内 ∆OFR 和 ∆FFR。FFR 和 OFR 的值分别为 0.89±0.06 和 0.90±0.06。OFR 与 FFR 高度相关（r=0.84，P<0.001）。OFR 与 FFR 具有良好的一致性，平均差值和均方根偏差较小（FFR-OFR：-0.01±0.04）。支架内 ∆OFR 与支架内 ∆FFR 具有中度相关性（r=0.69，P<0.001）和良好的一致性（支架内 ∆FFR - 支架内 ∆OFR：0.00±0.02）。
结论
OFR 在 PCI 后即刻支架治疗的动脉中与 FFR 具有高度相关性和良好的一致性。
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