University of Milano-Bicocca, ASST Monza, San Gerardo Hospital, Monza, Italy.
ASST Santi Paolo e Carlo, San Paolo Hospital, Milan, Italy.
Low Urin Tract Symptoms. 2021 Apr;13(2):257-263. doi: 10.1111/luts.12362. Epub 2020 Oct 28.
To evaluate the incidence and assess clinical factors that can predict the occurrence of postpartum urinary retention (PPUR). PPUR is a puerperal condition defined as the inability to void over 6 hours after birth or after catheter removal in case of cesarean section, requiring catheterization. Lack of prompt diagnosis of this condition may lead to severe sequelae, including infection, chronic voiding difficulties, and renal failure.
This retrospective cohort study analyzed all deliveries from January 2011 to December 2017 in a single Italian university hospital. We used multivariate logistic regression to develop a predictive score for PPUR.
By multivariate logistic regression, our analysis shows as minor (odds ratio [OR] < 2) risk factors for PPUR: non-Caucasian ethnicity (OR = 1.46, CI = 1.05-2.03), nulliparity (OR = 1.47, CI = 1.01-2.14), body mass index (BMI) at the end of the pregnancy <30 kg/m (OR = 1.54, CI = 1.10-2.17). On the other hand, epidural analgesia (OR = 3.93, CI = 2.96-5.22), meconium-stained amniotic fluid (OR = 2.07, CI = 1.54-2.77), nonoperative vaginal birth vs cesarean section (OR = 6.25, CI = 2.16-18.13), vacuum extraction vs cesarean section (OR = 8.80, CI = 2.86-27.01), pushing stage ≥60 minutes (OR = 3.00,CI = 2.26-3.97), and perineal tear (OR = 2.87, CI = 1.86-4.43) proved to be major (OR > 2) risk factors for PPUR. Using our final model (area under curve = 0.84), we created a nomogram for PPUR absolute risk calculation. Specifically, a 116-point cutoff might be used to identify high-risk patients who deserve more intensive micturition monitoring.
Our study identified non-Caucasian ethnicity, nulliparity, and a BMI <30 kg/m at the end of the pregnancy as minor and epidural analgesia, meconium-stained amniotic fluid, vaginal nonoperative birth, vacuum extraction, pushing stage ≥60 minutes, and perineal tear as major independent risk factors for PPUR.
评估产后尿潴留(PPUR)的发生率,并评估可预测其发生的临床因素。PPUR 是一种产后病症,定义为在自然分娩后 6 小时或剖宫产术后拔除导尿管后无法排尿,需要导尿。如果未能及时诊断出这种情况,可能会导致严重的后遗症,包括感染、慢性排尿困难和肾衰竭。
本回顾性队列研究分析了 2011 年 1 月至 2017 年 12 月期间意大利某家大学医院的所有分娩病例。我们使用多变量逻辑回归分析来建立 PPUR 的预测评分。
多变量逻辑回归分析显示,非白种人(比值比 [OR] < 2)、初产妇(OR = 1.47,95%置信区间 [CI] = 1.01-2.14)和孕晚期 BMI < 30kg/m(OR = 1.54,95%CI = 1.10-2.17)是发生 PPUR 的低危因素。另一方面,硬膜外镇痛(OR = 3.93,95%CI = 2.96-5.22)、羊水胎粪污染(OR = 2.07,95%CI = 1.54-2.77)、阴道分娩而非剖宫产(OR = 6.25,95%CI = 2.16-18.13)、产钳分娩而非剖宫产(OR = 8.80,95%CI = 2.86-27.01)、第二产程≥60 分钟(OR = 3.00,95%CI = 2.26-3.97)和会阴撕裂(OR = 2.87,95%CI = 1.86-4.43)是发生 PPUR 的高危因素(OR > 2)。基于我们的最终模型(曲线下面积 [AUC] = 0.84),我们创建了一个预测 PPUR 绝对风险的列线图。具体来说,我们可以使用 116 分作为截点来识别需要更密切监测排尿的高危患者。
本研究发现,非白种人、初产妇和孕晚期 BMI < 30kg/m 是发生 PPUR 的低危因素,而硬膜外镇痛、羊水胎粪污染、阴道非手术分娩、产钳分娩、第二产程≥60 分钟和会阴撕裂是发生 PPUR 的高危因素。