Department of Cardiovascular Surgery, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, Guangdong, China.
The First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Braz J Cardiovasc Surg. 2021 Feb 1;36(1):48-56. doi: 10.21470/1678-9741-2020-0115.
To evaluate the efficacy of hybrid transthoracic periventricular device closure of ventricular septal defects (VSDs) in a single center.
All patients who underwent hybrid transthoracic periventricular device closure of VSDs between January 2018 and December 2019 were retrospectively analyzed. The preoperative, operative and postoperative findings and clinical follow-ups were reviewed.
A total of 59 patients underwent the procedure. Transesophageal echocardiographic guidance was used in all procedures. The procedure was successful in 57 procedures (97%). The procedures of two patients were changed to openheart surgery during the same intervention due to severe aortic insufficiency (the device was not deployed) and significant residual shunt after device deployment. One major complication (1.7%) was observed after the procedure. The patient's device was dislodged within 12 hours after the procedure, and this patient underwent device extraction and VSD patch closure due to significant residual shunt. Eight (14%) minor complications were observed after the procedure, and three of them persisted during follow-up. Three of these eight complications were incomplete right bundle branch block, one of which resolved during followup; two were mild residual shunts, one of which resolved during follow-up; two were mild new-onset tricuspid valve insufficiencies; and one was mild new-onset mitral valve insufficiency; all valvular insufficiencies were resolved during follow-up.
Hybrid transthoracic periventricular device closure of VSD seems to be a good alternative approach due to its procedural success and low risk rates. The best advantage of the procedure is the possibility of switching to open-heart surgery, if necessary.
评估单中心应用杂交经胸体外循环室间隔缺损(VSD)封堵器治疗 VSD 的疗效。
回顾性分析 2018 年 1 月至 2019 年 12 月期间在我院接受杂交经胸体外循环室间隔缺损封堵术的所有患者。分析其术前、术中及术后发现和临床随访情况。
共 59 例行该手术。所有手术均采用经食管超声心动图引导。57 例(97%)手术成功。2 例患者因严重主动脉瓣关闭不全(封堵器未释放)和封堵器释放后仍有明显残余分流而改为同期开胸手术。术后观察到 1 例严重并发症(1.7%)。术后 12 小时患者封堵器脱落,因残余分流明显,再次行封堵器取出和 VSD 补片修补术。术后观察到 8 例(14%)轻度并发症,其中 3 例在随访期间持续存在。这 8 例并发症中,不完全性右束支传导阻滞 3 例,其中 1 例在随访中缓解;轻度残余分流 2 例,其中 1 例在随访中缓解;新发轻度三尖瓣关闭不全 2 例;新发轻度二尖瓣关闭不全 1 例;所有瓣膜关闭不全在随访中均得到缓解。
由于其手术成功率高、风险率低,杂交经胸体外循环室间隔缺损封堵术似乎是一种较好的治疗方法。该手术的最大优势是,如果需要,可随时转为开胸手术。