Adanacıoğlu Fatih, Tokat Zeynep Gözde, Büyükfidan Dürdane, Özgül Hanifi M, Urunsak Ferhat I, Çayan Selahittin, Çetin Turan M
Prof. Dr. M. Turan Çetin IVF Center, Adana, Turkey.
Adana City Hospital, Adana, Turkey.
Turk J Urol. 2019 Dec;45(Supp. 1):S7-S12. doi: 10.5152/tud.2019.99422. Epub 2019 Dec 1.
The aim of the present study was to analyze the success rates of frozen and fresh embryo transfer methods in different patient groups.
The study included 453 patients who underwent in vitro fertilization (IVF) treatment. The patients were further divided into three groups as male factor, tubal/ovarian/uterine factor, and other factors. IVF treatment was performed through either fresh or frozen embryo transfer (FET). Of the 453 patients, 298 had fresh embryo transfer, and 155 received FET. The implantation and live-birth rates of FET were compared with fresh transfer approach, focusing on the effects of male infertility.
There was a significant difference between the pregnancy ratios of patients who underwent fresh embryo transfer versus patients who underwent FET. In patients who were receiving IVF treatment due to male factors, the pregnancy rate was 49.32% in the fresh embryo transfer group, whereas it was 69.70% in the FET group, revealing a significant difference between the two groups (p=0.0321). Although the live-birth ratios were higher in the FET group both among all patients who underwent IVF due to male factor, the differences between the groups were not statistically significant.
We observed higher pregnancy rates in FET patients compared with fresh embryo transfer in the study group. The differences in pregnancy rates and live-birth rates were especially evident in IVF cases where male factor was the reason for the treatment.
本研究旨在分析不同患者群体中冷冻胚胎移植和新鲜胚胎移植方法的成功率。
该研究纳入了453例行体外受精(IVF)治疗的患者。患者进一步分为三组:男性因素组、输卵管/卵巢/子宫因素组和其他因素组。IVF治疗通过新鲜胚胎移植或冷冻胚胎移植(FET)进行。在453例患者中,298例行新鲜胚胎移植,155例接受FET。比较FET与新鲜移植方法的着床率和活产率,重点关注男性不育的影响。
接受新鲜胚胎移植的患者与接受FET的患者的妊娠率之间存在显著差异。在因男性因素接受IVF治疗的患者中,新鲜胚胎移植组的妊娠率为49.32%,而FET组为69.70%,两组之间存在显著差异(p = 0.0321)。尽管在所有因男性因素接受IVF的患者中,FET组的活产率均较高,但两组之间的差异无统计学意义。
在研究组中,我们观察到FET患者的妊娠率高于新鲜胚胎移植患者。妊娠率和活产率的差异在因男性因素导致治疗的IVF病例中尤为明显。