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本文引用的文献

1
Theory about the Embryo Cryo-Treatment.胚胎冷冻治疗理论。
Reprod Med Biol. 2017 Apr 5;16(2):118-125. doi: 10.1002/rmb2.12027. eCollection 2017 Apr.
2
Freeze-only in vitro fertilization cycles for all?所有人都采用仅冷冻的体外受精周期?
Fertil Steril. 2017 Aug;108(2):233-234. doi: 10.1016/j.fertnstert.2017.06.028.
3
Freeze-only versus fresh embryo transfer in a multicenter matched cohort study: contribution of progesterone and maternal age to success rates.仅冷冻胚胎与新鲜胚胎移植在多中心匹配队列研究中的比较:孕激素和母亲年龄对成功率的影响。
Fertil Steril. 2017 Aug;108(2):254-261.e4. doi: 10.1016/j.fertnstert.2017.05.007. Epub 2017 Jun 1.
4
Fresh versus frozen embryo transfers in assisted reproduction.辅助生殖中新鲜胚胎移植与冷冻胚胎移植的比较。
Cochrane Database Syst Rev. 2017 Mar 28;3(3):CD011184. doi: 10.1002/14651858.CD011184.pub2.
5
Fresh versus Frozen Embryos for Infertility in the Polycystic Ovary Syndrome.新鲜胚胎与冷冻胚胎在多囊卵巢综合征不孕中的应用。
N Engl J Med. 2016 Aug 11;375(6):523-33. doi: 10.1056/NEJMoa1513873.
6
Clinical outcomes following cryopreservation of blastocysts by vitrification or slow freezing: a population-based cohort study.玻璃化或慢速冷冻法冻存囊胚后的临床结局:一项基于人群的队列研究。
Hum Reprod. 2014 Dec;29(12):2794-801. doi: 10.1093/humrep/deu246. Epub 2014 Oct 14.
7
Clinical rationale for cryopreservation of entire embryo cohorts in lieu of fresh transfer.冷冻保存整批胚胎以替代新鲜胚胎移植的临床依据。
Fertil Steril. 2014 Jul;102(1):3-9. doi: 10.1016/j.fertnstert.2014.04.018. Epub 2014 May 17.
8
The use of in vitro fertilization in the management of male infertility: what the urologist needs to know.体外受精在男性不育症治疗中的应用:泌尿科医生需要了解的内容。
Rev Urol. 2013;15(4):154-60.
9
The epidemiology of male infertility.男性不育的流行病学。
Urol Clin North Am. 2014 Feb;41(1):195-204. doi: 10.1016/j.ucl.2013.08.006. Epub 2013 Sep 13.
10
Fresh embryo transfer versus frozen embryo transfer in in vitro fertilization cycles: a systematic review and meta-analysis.新鲜胚胎移植与体外受精周期中的冷冻胚胎移植:系统评价和荟萃分析。
Fertil Steril. 2013 Jan;99(1):156-162. doi: 10.1016/j.fertnstert.2012.09.003. Epub 2012 Oct 3.

体外受精中男性不育病例冷冻胚胎移植的更高效率

Higher efficiency of frozen embryo transfer in male infertility cases in in vitro fertilization.

作者信息

Adanacıoğlu Fatih, Tokat Zeynep Gözde, Büyükfidan Dürdane, Özgül Hanifi M, Urunsak Ferhat I, Çayan Selahittin, Çetin Turan M

机构信息

Prof. Dr. M. Turan Çetin IVF Center, Adana, Turkey.

Adana City Hospital, Adana, Turkey.

出版信息

Turk J Urol. 2019 Dec;45(Supp. 1):S7-S12. doi: 10.5152/tud.2019.99422. Epub 2019 Dec 1.

DOI:10.5152/tud.2019.99422
PMID:33120002
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7595027/
Abstract

OBJECTIVE

The aim of the present study was to analyze the success rates of frozen and fresh embryo transfer methods in different patient groups.

MATERIAL AND METHODS

The study included 453 patients who underwent in vitro fertilization (IVF) treatment. The patients were further divided into three groups as male factor, tubal/ovarian/uterine factor, and other factors. IVF treatment was performed through either fresh or frozen embryo transfer (FET). Of the 453 patients, 298 had fresh embryo transfer, and 155 received FET. The implantation and live-birth rates of FET were compared with fresh transfer approach, focusing on the effects of male infertility.

RESULTS

There was a significant difference between the pregnancy ratios of patients who underwent fresh embryo transfer versus patients who underwent FET. In patients who were receiving IVF treatment due to male factors, the pregnancy rate was 49.32% in the fresh embryo transfer group, whereas it was 69.70% in the FET group, revealing a significant difference between the two groups (p=0.0321). Although the live-birth ratios were higher in the FET group both among all patients who underwent IVF due to male factor, the differences between the groups were not statistically significant.

CONCLUSION

We observed higher pregnancy rates in FET patients compared with fresh embryo transfer in the study group. The differences in pregnancy rates and live-birth rates were especially evident in IVF cases where male factor was the reason for the treatment.

摘要

目的

本研究旨在分析不同患者群体中冷冻胚胎移植和新鲜胚胎移植方法的成功率。

材料与方法

该研究纳入了453例行体外受精(IVF)治疗的患者。患者进一步分为三组:男性因素组、输卵管/卵巢/子宫因素组和其他因素组。IVF治疗通过新鲜胚胎移植或冷冻胚胎移植(FET)进行。在453例患者中,298例行新鲜胚胎移植,155例接受FET。比较FET与新鲜移植方法的着床率和活产率,重点关注男性不育的影响。

结果

接受新鲜胚胎移植的患者与接受FET的患者的妊娠率之间存在显著差异。在因男性因素接受IVF治疗的患者中,新鲜胚胎移植组的妊娠率为49.32%,而FET组为69.70%,两组之间存在显著差异(p = 0.0321)。尽管在所有因男性因素接受IVF的患者中,FET组的活产率均较高,但两组之间的差异无统计学意义。

结论

在研究组中,我们观察到FET患者的妊娠率高于新鲜胚胎移植患者。妊娠率和活产率的差异在因男性因素导致治疗的IVF病例中尤为明显。