评估铅笔束扫描质子治疗肺部肿瘤时连续束扫描与脉冲束扫描的效果。
Evaluation of continuous beam rescanning versus pulsed beam in pencil beam scanned proton therapy for lung tumours.
机构信息
Department of Radiation Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Ion Beam Applications, Advanced Technology Group, Louvain-la-Neuve, Belgium.
出版信息
Phys Med Biol. 2020 Dec 18;65(23):23NT01. doi: 10.1088/1361-6560/abc5c8.
The treatment of moving targets with pencil beam scanned proton therapy (PBS-PT) may rely on rescanning strategies to smooth out motion induced dosimetric disturbances. PBS-PT machines, such as Proteus®Plus (PPlus) and Proteus®One (POne), deliver a continuous or a pulsed beam, respectively. In PPlus, scaled (or no) rescanning can be applied, while POne implies intrinsic 'rescanning' due to its pulsed delivery. We investigated the efficacy of these PBS-PT delivery types for the treatment of lung tumours. In general, clinically acceptable plans were achieved, and PPlus and POne showed similar effectiveness.
笔形束扫描质子治疗（PBS-PT）治疗移动靶区可能依赖于重扫描策略来平滑运动引起的剂量学干扰。PBS-PT 设备，如 Proteus®Plus（PPlus）和 Proteus®One（POne），分别提供连续或脉冲束。在 PPlus 中，可以应用缩放（或不应用）重扫描，而由于其脉冲输送，POne 意味着内在的“重扫描”。我们研究了这些 PBS-PT 输送类型治疗肺部肿瘤的效果。通常，可以实现临床可接受的计划，并且 PPlus 和 POne 显示出相似的效果。
Zotero 插件