Poulias G E, Skoutas B, Doundoulakis N, Prombonas E, Papaioannou K, Sendegeya S
Department of Thoracic and Cardiovascular Surgery, Red Cross General Hospital, Athens, Greece.
J Cardiovasc Surg (Torino). 1987 Nov-Dec;28(6):688-94.
Thirty five patients who underwent simultaneous aortic and renal artery reconstruction are reviewed, to determine the value of the combined approach. The risk factors determining operative morbidity and mortality are discussed, on the basis of a long term follow-up of more than sixteen years. All patients had a significant renal artery stenosis, in addition to either severe aorto-iliac occlusive disease or an abdominal aortic aneurysm. Twenty seven patients were hypertensive, and eight patients normotensive. Combined aorto-renal reconstruction was carried out prophylactically in eight instances. There were two operative deaths (5.7%). Factors found to be associated with an increased operative risk were advanced age (over 65 years), heart disease with ECG changes, severe hypertension and diabetes. Renal insufficiency with azothaemia and high levels of creatinine, represented a major risk factor. Post operatively, six individuals (24%) were classified as "cured" and thirteen (523) were "improved". Patients with bilateral renal artery stenosis, mild azothemia and moderately elevated creatinine, were found to improve significantly their renal function post operatively. No patient required hemodialysis. Simultaneous aorto-renal reconstruction may be performed with a low mortality and gratifying improvement in hypertensive patients, without evidence of adverse features.
回顾了35例同时进行主动脉和肾动脉重建的患者,以确定联合手术方法的价值。在超过16年的长期随访基础上,讨论了决定手术发病率和死亡率的危险因素。所有患者除患有严重的主-髂动脉闭塞性疾病或腹主动脉瘤外,均有明显的肾动脉狭窄。27例患者患有高血压,8例血压正常。8例进行了预防性的主动脉-肾联合重建。有2例手术死亡(5.7%)。发现与手术风险增加相关的因素有高龄(65岁以上)、有心电图改变的心脏病、严重高血压和糖尿病。伴有氮质血症和高肌酐水平的肾功能不全是一个主要危险因素。术后,6人(24%)被归类为“治愈”,13人(52%)“病情改善”。发现双侧肾动脉狭窄、轻度氮质血症和肌酐中度升高的患者术后肾功能有明显改善。没有患者需要血液透析。同时进行主动脉-肾重建手术死亡率低,能使高血压患者病情明显改善,且无不良表现。