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腹主动脉肾旁动脉瘤的管理

Management of pararenal aneurysms of the abdominal aorta.

作者信息

Qvarfordt P G, Stoney R J, Reilly L M, Skioldebrand C G, Goldstone J, Ehrenfeld W K

出版信息

J Vasc Surg. 1986 Jan;3(1):84-93. doi: 10.1067/mva.1986.avs0030084.

Abstract

The operative treatment of 77 patients with atherosclerotic aneurysms of the pararenal aorta (54 juxtarenal and 23 suprarenal) is analyzed. Repair of these complex lesions is formidable because of difficult exposure, renal ischemia and myocardial strain as a result of proximal aortic occlusion, and associated renal atherosclerosis with secondary renal functional impairment. Nineteen (25%) patients were normotensive with normal renal function. Sixteen patients (21%) had hypertension alone and 42 (54%) were hypertensive with abnormal renal function. There were multiple renal arteries in 22% of patients. Aortic reconstruction involved infrarenal graft in 27 patients (35%), infrarenal graft plus pararenal aortic endarterectomy (TEA) in 26 (34%), and infra- and pararenal aortic graft in 24 (31%). Twenty-two patients (30%) had normal renal arteries and therefore no renal reconstruction. Of the 55 patients who required combined aortic and renal artery repair, 24 required renal artery repair because of involvement of the renal arteries by the aneurysm and 31 because of atherosclerotic renal artery disease. TEA was the most common technique of renal artery repair (54 of 93 arteries, 58%), followed by reimplantation (18 arteries) and prosthetic graft (13). The perioperative mortality rate was 1.3%. The perioperative morbidity rate was 28% and consisted principally of renal insufficiency (23%). This was usually transient (44%) and (89%) mild. Renal morbidity was adversely affected by renal ischemia status, severity of renal artery disease and extent of renal revascularization. Following reconstruction, hypertension was cured or improved in 77% of patients and abnormal renal function was cured or improved in 46% and stabilized in an additional 39% of patients. These results show that combined aortic aneurysm repair and renal artery reconstruction can be performed with minimal mortality and an acceptable morbidity. Aggressive intraoperative monitoring is necessary to minimize myocardial complications. Careful attention must be paid to the technical details of the reconstruction, especially in minimizing renal ischemia, to reduce the subsequent incidence of renal function deterioration.

摘要

对77例肾旁主动脉粥样硬化性动脉瘤患者(54例近肾型和23例肾上型)的手术治疗进行了分析。由于暴露困难、近端主动脉阻断导致的肾缺血和心肌劳损,以及相关的肾动脉粥样硬化伴继发性肾功能损害,修复这些复杂病变具有挑战性。19例(25%)患者血压正常且肾功能正常。16例(21%)患者仅有高血压,42例(54%)患者高血压且肾功能异常。22%的患者存在多条肾动脉。主动脉重建包括27例(35%)患者采用肾下移植,26例(34%)患者采用肾下移植加肾旁主动脉内膜切除术(TEA),24例(31%)患者采用肾下和肾旁主动脉移植。22例(30%)患者肾动脉正常,因此无需进行肾重建。在55例需要联合主动脉和肾动脉修复的患者中,24例因动脉瘤累及肾动脉而需要肾动脉修复,31例因动脉粥样硬化性肾动脉疾病而需要肾动脉修复。TEA是最常见的肾动脉修复技术(93条动脉中的54条,58%),其次是再植术(18条动脉)和人工血管移植(13条)。围手术期死亡率为1.3%。围手术期发病率为28%,主要包括肾功能不全(23%)。这通常是短暂的(44%),且(89%)为轻度。肾缺血状态、肾动脉疾病的严重程度和肾血运重建的范围对肾脏发病率有不利影响。重建后,77%的患者高血压得到治愈或改善,46%的患者肾功能异常得到治愈或改善,另有39%的患者肾功能稳定。这些结果表明,联合主动脉瘤修复和肾动脉重建可以在最低死亡率和可接受的发病率下进行。积极的术中监测对于将心肌并发症降至最低是必要的。必须仔细注意重建的技术细节,特别是在尽量减少肾缺血方面,以降低随后肾功能恶化的发生率。

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