Department of Anatomy, Faculty of Veterinary Medicine, University of Belgrade, Serbia.
Department of Radiology and Radiation Hygiene, Faculty of Veterinary Medicine, University of Belgrade, Serbia.
Folia Morphol (Warsz). 2021;80(4):888-894. doi: 10.5603/FM.a2020.0132. Epub 2020 Oct 30.
There are many studies on the morphology of the liver and its blood vessels in experimental animals, but such studies are lacking in the mole rat (Spalax leucodon). The aim of this paper was a detailed basic study on the topography, morphology, vascular and biliary branching systems of the liver in the mole rat.
Coloured gelatine and mixture of coloured lead oxide and linseed oil were injection contrast masses used to obtain vascular and biliary branching pattern in the liver. It was revealed that the liver of the mole rat had five lobes (left, quadrate, right medial, right lateral and caudate lobes).
The left, undivided lobe was the largest lobe of the liver. The quadrate lobe was divided into two components by a deep notch. The gallbladder, of cylindrical shape, was present and attached to the quadrate lobe. The common bile duct was formed by the union of the left and right hepatic ducts. The pancreatic duct joined the common bile duct before it entered the duodenum. In the present study, only the right medial lobe and quadrate lobe always showed a single lobar artery, portal and hepatic veins. The left lobe showed four lobar arteries, portal and hepatic veins. The caudate lobe with its two processes and the right lateral and medial lobes had different arterial and portal blood supply as well as hepatic and biliary drainage of these lobes. The intrahepatic branches of the proper hepatic artery ran parallel to the branches of the common portal vein in the same lobes of the liver.
The results of this study are significant for comparative studies among different species of rodents and other experimental animals. Morphology, vasculature and biliary tract of the liver in the mole rat were similar to that of other experimental animals and identified differences may be related to the adaptation to the mode of life and diet of this rodent.
已有许多关于实验动物肝脏及其血管形态学的研究，但在鼹形田鼠（Spalax leucodon）中却缺乏此类研究。本研究旨在详细研究鼹形田鼠肝脏的表面解剖、形态、血管和胆支系统。
采用彩色明胶和彩色氧化铅与亚麻籽油混合物作为注射对比剂，以获得肝脏的血管和胆支系统分支模式。结果表明，鼹形田鼠的肝脏有 5 个叶（左叶、方叶、右中叶、右外侧叶和尾叶）。
未分隔的左叶是肝脏最大的叶。方叶被一个深裂分为两部分。胆囊呈圆柱形，附着在方叶上。胆总管由左、右肝管汇合而成。胰管在进入十二指肠之前与胆总管汇合。在本研究中，只有右中叶和方叶始终显示单一的叶动脉、门静脉和肝静脉。左叶显示 4 个叶动脉、门静脉和肝静脉。尾叶及其两个突起和右外侧叶与内侧叶具有不同的动脉和门静脉血供以及这些叶的肝和胆引流。肝固有动脉的肝内分支与同一肝叶内的门静脉分支平行。
本研究结果对不同种属啮齿动物和其他实验动物的比较研究具有重要意义。鼹形田鼠肝脏的形态、血管和胆系与其他实验动物相似，所识别的差异可能与该啮齿动物的生活方式和饮食适应有关。
