Aydın Efruz Pirdoğan, Kenar Jülide Güler, Tutan Aslı, Akil Özer Ömer, Oğuz Karamustafalıoğlu Kayıhan
Department of Psychiatry, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.
Clin Psychopharmacol Neurosci. 2020 Nov 30;18(4):631-635. doi: 10.9758/cpn.2020.18.4.631.
Trichotillomania is a psychiatric disorder characterised by compulsive pulling out of one's hair resulting in hair loss, which is included in the Diagnostic and Statistical Manual of Mental Disorders 5th edition category 'obsessive-compulsive disorder and related disorders'. Behavioural therapy and some medications are suggested for the treatment of trichotillomania, though these are not effective for all patients. Therefore, new treatment options are needed. Five female patients diagnosed with trichotillomania applied low-frequency repetitive transcranial magnetic stimulation (rTMS) over bilateral supplementary motor area for 3 weeks. Baseline and after rTMS, patients were given Beck Depression Inventory, Beck Anxiety Inventory and Massachusetts General Hospital Hair Pulling Scale to evaluate the severity of disorder at baseline and post-rTMS. In this case series, three of five patients with trichotillomania obtained a substantial benefit from treatment, while one patient obtained a partial symptom reduction. The last patient experienced a mild increase in severity of disease after rTMS treatment. rTMS treatment can be effective in some patients with trichotillomania and can be a promising option in treatment of trichotillomania.
拔毛癖是一种精神疾病，其特征是强迫性地拔自己的头发导致脱发，它被列入《精神疾病诊断与统计手册》第5版中的“强迫症及相关障碍”类别。行为疗法和一些药物被建议用于治疗拔毛癖，不过这些对所有患者并非都有效。因此，需要新的治疗选择。五名被诊断为拔毛癖的女性患者在双侧辅助运动区进行了为期3周的低频重复经颅磁刺激（rTMS）。在rTMS治疗前和治疗后，患者接受了贝克抑郁量表、贝克焦虑量表和麻省总医院拔毛量表评估，以评估治疗前和rTMS治疗后的疾病严重程度。在这个病例系列中，五名拔毛癖患者中有三名从治疗中获得了显著益处，一名患者症状部分减轻。最后一名患者在rTMS治疗后疾病严重程度略有增加。rTMS治疗对一些拔毛癖患者可能有效，并且可能是治疗拔毛癖的一个有前景的选择。
