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顶点主动脉旁路中血流分配和移植物设计的计算流体动力学模拟。

Computational fluid dynamics simulations of flow distribution and graft designs in apicoaortic bypass.

机构信息

Department of Cardiovascular Surgery, Nippon Medical School, 1-1-5, Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.

Department of Cardiovascular Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.

出版信息

Gen Thorac Cardiovasc Surg. 2021 May;69(5):811-818. doi: 10.1007/s11748-020-01527-8. Epub 2020 Oct 30.

Abstract

OBJECTIVE

Apicoaortic bypass has double outlets and its graft design is similar to that of a left ventricular assist device (LVAD). The left ventricular apex to the descending aorta (LV-DsAo) bypass is widely used in apicoaortic bypass. In contrast, the left ventricular apex to the ascending aorta (LV-AsAo) bypass is standard in LVAD surgery. This study aimed to evaluate the graft designs of apicoaortic bypass and their effects on flow distribution and energy loss (EL).

METHODS

A simulation study using computational fluid dynamics was performed on the geometry and hemodynamics data obtained from a 30-year-old patient who underwent a LV-DsAo bypass. The ratio of the cardiac output (CO) through the ascending aorta (AsAo) and apicoaortic conduit was set at 50:50, 30:70, and 10:90. Regional blood flow (RBF) and EL were calculated for the different distribution ratios. As an alternative to the LV-DsAo bypass, a virtual LV-AsAo bypass surgery was performed, and each parameter was compared with that of the LV-DsAo bypass.

RESULTS

At a distribution ratio of 50:50, the RBF to the head and EL were 16.4% of the total CO and 62.0 mW in the LV-DsAo bypass, and 32.3% and 81.5 mW in the LV-AsAo bypass, respectively. The RBF to the head decreased with the CO through the AsAo in the LV-DsAo bypass, but it was constant in the LV-AsAo bypass. The EL increased inversely with the CO through the AsAo in both graft designs.

CONCLUSION

The regional blood flow distribution was different, but the trend of the EL which increased inversely with the CO through the AsAo was similar between the LV-DsAo and LV-AsAo bypasses.

摘要

目的

主动脉瓣下旁路有两个流出道,其移植物设计类似于左心室辅助装置(LVAD)。左心室心尖至降主动脉(LV-DsAo)旁路在主动脉瓣下旁路中广泛应用。相比之下,左心室心尖至升主动脉(LV-AsAo)旁路是 LVAD 手术中的标准方法。本研究旨在评估主动脉瓣下旁路的移植物设计及其对血流分布和能量损失(EL)的影响。

方法

使用计算流体动力学对一名 30 岁接受 LV-DsAo 旁路手术的患者的几何形状和血液动力学数据进行模拟研究。将通过升主动脉(AsAo)和主动脉瓣下导管的心脏输出(CO)的比例设定为 50:50、30:70 和 10:90。计算了不同分布比例下的局部血流(RBF)和 EL。作为 LV-DsAo 旁路的替代方案,进行了虚拟 LV-AsAo 旁路手术,并将每个参数与 LV-DsAo 旁路进行了比较。

结果

在 50:50 的分布比例下,LV-DsAo 旁路中头部的 RBF 和 EL 分别为总 CO 的 16.4%和 62.0 mW,LV-AsAo 旁路中头部的 RBF 和 EL 分别为 32.3%和 81.5 mW。在 LV-DsAo 旁路中,随着 CO 通过 AsAo 的增加,头部的 RBF 减少,但在 LV-AsAo 旁路中,RBF 保持不变。EL 与两种移植物设计中 CO 通过 AsAo 的增加呈反比增加。

结论

两种旁路的区域血流分布不同,但 EL 随 CO 通过 AsAo 的增加而反向增加的趋势相似。

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