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经肛门管状吻合器在预防前切除术吻合口漏中的作用:系统评价和荟萃分析。

The impact of transanal tube design for preventing anastomotic leak in anterior resection: a systematic review and meta-analysis.

机构信息

Department of Surgery, University of Auckland, Auckland Hospital Clinical Support Block, 2 Park Rd, Grafton, Auckland, 1023, New Zealand.

出版信息

Tech Coloproctol. 2021 Jan;25(1):59-68. doi: 10.1007/s10151-020-02354-y. Epub 2020 Oct 30.

Abstract

BACKGROUND

Placement of a transanal tube (TAT) into the rectum is a strategy used to attempt to prevent anastomotic leak (AL) in anterior resection surgery. There is a wide variation in materials and tube design in devices used as TATs and previous meta-analyses have not considered TAT design in their analyses. This study reviews the impact that design of TAT has on AL rates.

METHODS

A systematic review of the literature was performed with the aim of identifying studies evaluating the use of TATs for preventing AL and then defining the design of TATs. Studies were then compared in groups based on TAT design in a meta-analysis to evaluate whether design is an important variable in outcomes.

RESULTS

Thirty-three studies were included. There was a wide variety of tubes used as TATs. On meta-analysis, catheter-type TATs were associated with a substantially lower rate of AL (OR: 0.46; 95% CI 0.30, 0.68). By contrast, stent-type TATs were not associated with any reduction in the incidence of AL (OR: 1.06, 95% CI 0.50, 2.22). Catheter-type TATs were also associated with substantial reductions in the rate of reoperation (OR: 0.32; 95% CI 0.20, 0.50), whereas stent-type TATs showed no benefit in the rate of reoperation (OR: 0.79; 95% CI 0.37, 1.65).

CONCLUSIONS

Off-the-shelf catheter-type transanal tubes appeared effective in preventing AL, whereas custom-designed stent-type TATs were not demonstrated to be effective; although high quality evidence is limited. TAT design should be an important consideration in further research of the use of TATs in anterior resection surgery.

摘要

背景

经肛门管(TAT)置入直肠是一种用于尝试预防前切除术吻合口漏(AL)的策略。在用于 TAT 的装置中,材料和管设计存在广泛的差异,并且之前的荟萃分析并未在其分析中考虑 TAT 设计。本研究综述了 TAT 设计对 AL 发生率的影响。

方法

对文献进行系统评价,旨在确定评估 TAT 用于预防 AL 的研究,然后定义 TAT 的设计。然后在荟萃分析中根据 TAT 设计将研究分为组进行比较,以评估设计是否是结果的重要变量。

结果

共纳入 33 项研究。用作 TAT 的管有多种。在荟萃分析中,导管型 TAT 与 AL 发生率显著降低相关(OR:0.46;95%CI 0.30,0.68)。相比之下,支架型 TAT 与 AL 发生率降低无关(OR:1.06,95%CI 0.50,2.22)。导管型 TAT 还与手术再干预率的显著降低相关(OR:0.32;95%CI 0.20,0.50),而支架型 TAT 则不能降低手术再干预率(OR:0.79;95%CI 0.37,1.65)。

结论

现成的导管型 TAT 似乎能有效预防 AL,而定制的支架型 TAT 则无效;尽管高质量证据有限。TAT 设计应成为进一步研究 TAT 在前切除术应用中的重要考虑因素。

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