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线性口周萎缩性皮肤病沿 Blaschko 线分布——一项回顾性研究描述了 14 例痘疮样皮肤萎缩性苔藓。

Linear perioral atrophoderma along blaschko's lines- a retrospective study describing 14 cases of atrophia maculosa varioliformis cutis.

机构信息

Department of Dermatology, Dr. RPGMC, Kangra, India.

Department of Dermatology, IGMC, Shimla, India.

出版信息

Australas J Dermatol. 2021 Feb;62(1):e62-e66. doi: 10.1111/ajd.13457. Epub 2020 Oct 30.

DOI:10.1111/ajd.13457
PMID:33125705
Abstract

BACKGROUND

Spontaneous atrophic scarring is characterised by an idiopathic, non-inflammatory macular atrophy that typically occurs on the face and presents as shallow atrophic scars having sharp margins and may be linear, rectangular or varioliform.

AIM

To describe the cases of spontaneous atrophic scarring over perioral region of face having specific feline band pattern in a retrospective study.

MATERIALS AND METHODS

All patients with facial atrophoderma (perioral region) were evaluated clinically and histopathologically in tertiary care centres over 3 years. Patients with facial atrophoderma but no perioral involvement and secondary atrophoderma were excluded from the study. Patients were evaluated for number, sites, size and shape of lesions and were confirmed histopathologically.

RESULTS

There were 14 patients (10 females) with facial atrophoderma particularly over the perioral region. Three patients had perioral involvement with a few lesions on the cheeks and forehead. All patients developed atrophoderma spontaneously without preceding inflammation. Most of the patients were asymptomatic except for mild pain or burning at the time of development of atrophic lesions; however, none of the patients were symptomatic at the time of presentation. Histopathology in 5 patients showed epidermal and upper dermal atrophy with no/minimal signs of inflammation.

CONCLUSION

Idiopathic atrophodermas over the face can be due to spontaneous atrophia maculosa varioliformis cutis or atrophoderma of Moulin.

摘要

背景

自发性萎缩性瘢痕的特征为特发性、非炎症性黄斑萎缩,通常发生在面部,表现为边界锐利的浅层萎缩性瘢痕,可能呈线性、矩形或痘疮样。

目的

在回顾性研究中描述面部口周区域自发性萎缩性瘢痕具有特定猫带模式的病例。

材料和方法

在 3 年的时间里,在三级护理中心对所有患有面部萎缩性皮肤病(口周区域)的患者进行了临床和组织病理学评估。患有面部萎缩性皮肤病但无口周受累和继发性萎缩性皮肤病的患者被排除在研究之外。对患者的病变数量、部位、大小和形状进行评估,并通过组织病理学进行确认。

结果

有 14 名患者(10 名女性)患有面部萎缩性皮肤病,特别是口周区域。3 名患者口周受累,面颊和额头上有几个病变。所有患者均自发性发生萎缩性皮肤病,无先前炎症。大多数患者无症状,除了在萎缩性病变发生时出现轻微疼痛或烧灼感;然而,在就诊时没有患者出现症状。5 名患者的组织病理学表现为表皮和上部真皮萎缩,无/仅有最小的炎症迹象。

结论

面部特发性萎缩性皮肤病可能是由于自发性黄斑萎缩性痘疮样皮肤或穆林萎缩性皮肤病引起的。

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Australas J Dermatol. 2021 Feb;62(1):e62-e66. doi: 10.1111/ajd.13457. Epub 2020 Oct 30.
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