Department of Cytology and Gynaecological Pathology, Post Graduate Institute of Medical Education & Research, Chandigarh, India.
Cytopathology. 2021 Mar;32(2):233-237. doi: 10.1111/cyt.12934. Epub 2020 Nov 30.
Any type of cutaneous metastasis indicates dismal outcome of the disease. Skin is an unusual location for metastatic deposits from any tumour and has an incidence of about 0.8%-5%. Fine needle aspiration cytology (FNAC) helps in the rapid diagnosis of metastasis with minimum pain.
To study the cytomorphological spectrum of cutaneous metastasis on FNAC.
A total of 225 patients with diagnosis of cutaneous metastasis on cytology were analysed. May-Grünwald Giemsa and haematoxylin-eosin-stained smears were studied and examined for the cytomorphological spectrum of cutaneous metastasis. Cell block was prepared in a few cases. In a subset of cases, immunohistochemistry was done to pinpoint the primary.
Amongst the 225 patients studied, the mean age was 53.9 years. There was female preponderance with 125 females and 100 males. The commonest site was abdominal wall (n = 89) followed by chest wall (n = 60). The most common type of metastasising tumour was adenocarcinoma.
Clinicians and pathologists must be aware of the clinico-morphological spectrum of cutaneous metastasis for instant diagnosis followed by prompt management.
任何类型的皮肤转移都表明疾病预后不良。皮肤是任何肿瘤转移灶的罕见部位，其发生率约为 0.8%-5%。细针抽吸细胞学（FNAC）有助于在最小的疼痛下快速诊断转移。
研究 FNAC 上皮肤转移的细胞形态学谱。
共分析了 225 例细胞学诊断为皮肤转移的患者。对 May-Grünwald Giemsa 和苏木精-伊红染色的涂片进行了研究，并对皮肤转移的细胞形态学谱进行了检查。在少数情况下，还制备了细胞块。在亚组病例中，进行了免疫组织化学检查以确定原发灶。
在研究的 225 例患者中，平均年龄为 53.9 岁。女性居多，有 125 名女性和 100 名男性。最常见的部位是腹壁（n=89），其次是胸壁（n=60）。最常见的转移瘤类型是腺癌。
临床医生和病理学家必须了解皮肤转移的临床形态学谱，以便即时诊断，随后进行及时治疗。
