Faculty of Medicine, Ophthalmology Department, Suez Canal University, Ring Road, Ismailia, Egypt.
Graefes Arch Clin Exp Ophthalmol. 2021 Mar;259(3):777-786. doi: 10.1007/s00417-020-04990-4. Epub 2020 Oct 31.
To assess the relationship between the axial length and post-LASIK regression in myopic patients.
This is a retrospective case series study conducted at a private eye centre, Ismailia, Egypt. The clinical records of the patients, who experienced LASIK to correct myopia from January 2016 to January 2018, were analysed for myopic regression. The patients were operated on, examined, and followed-up 1 year by one surgeon (AAG).
This study included 1219 patients (2316 eyes) with myopia. Mean ± SD of pre-operative spherical equivalent (SE) was - 4.3 ± 2.1D, range (- 0.50 to - 10.0D). Mean ± SD age of the patients was 26.4 ± 6.8 years, range (21 to 50 years). Male to female ratio was 30.5 to 69.5%. The cumulative incidence rate of myopic regression according to the medical records of the patients was 25.12% (582 eyes out of total 2316 eyes) along the 2 years of this study (12.6% per year). Of the total patients, 14.94% had pre-operative high myopia, 35.84% had pre-operative moderate myopia, and 49.2% had pre-operative low myopia. Of the patients with myopic regression, 52.6% had pre-operative high myopia, 34% had pre-operative moderate myopia, and 13.4% had pre-operative low myopia. The mean ± SD of the axial length of the patients with myopic regression was 26.6 ± 0.44 mm, range (26.0 to 27.86 mm), while the mean ± SD of the axial length of other patients with stable refraction was 24.38 ± 0.73 mm, range (22.9 to 25.9 mm) (t test statistic = 69.3; P value < 0.001).
Pre-operative high axial length increases the risk of myopic regression after LASIK.
评估近视患者 LASIK 术后眼轴长度与回退的关系。
这是在埃及伊斯梅利亚的一家私人眼科中心进行的回顾性病例系列研究。分析了 2016 年 1 月至 2018 年 1 月接受 LASIK 治疗近视的患者的近视回退临床记录。由一位医生（AAG）进行手术、检查和术后 1 年随访。
本研究共纳入 1219 例（2316 只眼）近视患者。术前等效球镜（SE）的平均值±标准差为-4.3±2.1D，范围为-0.50 至-10.0D。患者的平均年龄±标准差为 26.4±6.8 岁，范围为 21 至 50 岁。男女比例为 30.5:69.5%。根据患者病历，本研究 2 年内近视回退的累积发生率为 25.12%（582 只眼占总 2316 只眼），每年为 12.6%。在所有患者中，术前高度近视占 14.94%，术前中度近视占 35.84%，术前低度近视占 49.2%。在有近视回退的患者中，术前高度近视占 52.6%，术前中度近视占 34%，术前低度近视占 13.4%。近视回退患者的平均眼轴长度±标准差为 26.6±0.44mm，范围为 26.0 至 27.86mm，而其他屈光稳定患者的平均眼轴长度±标准差为 24.38±0.73mm，范围为 22.9 至 25.9mm（t 检验统计量=69.3；P 值<0.001）。
术前高眼轴长度增加 LASIK 术后近视回退的风险。
