Pecher S A, Azevedo E B
Faculdade de Ciências da Saúde, Universidade do Amazonas, Manaus, Brasil.
Med Cutan Ibero Lat Am. 1987;15(3):239-42.
A study was made of twenty-two biopsies of achromic lesions of Tikuna Indians, carriers of tertiary pinta, inhabitants of the Umariuassu island, on the Peruvian border, ten of the subjects had been treated two years previously with a single dose of penicillin. The histopathological picture was similar for both groups. In most cases (86.36%) slight hyperkeratosis was found on the epidermis, as well as acanthosis (18.18%), with atrophy in only two cases (9.09%). In all cases there was a reduction of the melanin of the basal layer. The inflammatory lymphocyte infiltrate was predominantly perivascular (88.18%). There wasn't any endothelial swelling.
对秘鲁边境乌马里亚苏岛的提库纳印第安人（三期品他病携带者）的22例色素脱失性病变活检样本进行了研究。其中10名受试者在两年前接受过单剂量青霉素治疗。两组的组织病理学表现相似。在大多数病例（86.36%）中，表皮出现轻微角化过度，以及棘层肥厚（18.18%），仅有两例（9.09%）出现萎缩。所有病例中，基底层黑色素均减少。炎症性淋巴细胞浸润主要为血管周围浸润（88.18%）。未发现内皮肿胀。
