Graduate School of Human Health Sciences, Tokyo Metropolitan University, Japan; Faculty of Healthcare Sciences, Chiba Prefectural University of Health Sciences, Japan.
Graduate School of Human Health Sciences, Tokyo Metropolitan University, Japan.
Brain Cogn. 2020 Dec;146:105632. doi: 10.1016/j.bandc.2020.105632. Epub 2020 Oct 28.
Visual-motor illusion (VMI) is to evoke a kinesthetic sensation by viewing images of oneself performing physical exercise while the body is at rest. Previous studies demonstrated that VMI activates the motor association brain areas; however, it is unclear whether VMI immediately alters the resting-state functional connectivity (RSFC). This study is aimed to verify whether the VMI induction changed the RSFC using functional near-infrared spectroscopy (fNIRS). The right hands of 13 healthy adults underwent illusion and observation conditions for 20 min each. Before and after each condition, RSFC was measured using fNIRS. After each condition, degree of kinesthetic illusion and a sense of body ownership measured using the Likert scale. Our results indicated that, compared with the observation condition, the degree of kinesthetic illusion and the sense of body ownership were significantly higher after the illusion condition. Compared with the observation condition, RSFC after the illusion condition significantly increased brain areas associated with kinesthetic illusion, a sense of body ownership, and motor execution. In conclusion, RSFC has become a biomarker that shows changes in brain function occurring due to VMI. VMI may be applied to the treatment of patients with stroke or orthopedic diseases.
视动错觉（VMI）是指通过观看自己在静止状态下进行体育锻炼的图像来唤起运动感觉。先前的研究表明，VMI 会激活运动联想脑区；然而，VMI 是否会立即改变静息状态功能连接（RSFC）尚不清楚。本研究旨在使用近红外光谱（fNIRS）验证 VMI 诱导是否改变了 RSFC。13 名健康成年人的右手分别接受了 20 分钟的错觉和观察条件。在每个条件之前和之后，使用 fNIRS 测量 RSFC。在每个条件之后，使用李克特量表测量运动错觉的程度和身体所有权的感觉。我们的结果表明，与观察条件相比，错觉条件后运动错觉的程度和身体所有权的感觉明显更高。与观察条件相比，错觉条件后的 RSFC 显著增加了与运动错觉、身体所有权和运动执行相关的脑区。总之，RSFC 已成为一种生物标志物，可显示因 VMI 而导致的大脑功能变化。VMI 可能应用于治疗中风或骨科疾病患者。
