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[热带地区女性感染艾滋病毒所带来的问题]

[Problems posed by HIV infection in women in tropical zones].

作者信息

Coulaud J P, Pradinaud R, Liautaud B

机构信息

Hôpital Claude-Bernard, Paris.

出版信息

Med Trop (Mars). 1987 Jul-Sep;47(3):279-85.

PMID:3312923
Abstract

Retroviruses (mainly H.I.V. 1 and H.I.V. 2) are now largely spread over in Central Africa and Caribbean Islands, particularly in large cities. Their transmission is essentially horizontal and mainly sexual. As a matter of fact, sexual transmission is responsible in about 80% of the cases, leaving only a small percentage to transmission by needle (or by any aggressive material), blood or blood by-products. As far as sexual transmission is concerned, it is essentially heterosexual, in spite of the primary epidemic outbreak in the occidental world that focused interest toward male homosexual group, the first exposed to A.I.D.S. Nowadays we know that heterosexual transmission is important and bi-directionnal, even if transmission female to male has seemed to be more difficult to enlight, as it is common in sexually transmitted diseases. Transmission risk to an heterosexual partner is between 20 and 70%. Virus is present in semen, and in cervico-vaginalis secretions during all menstruation cycle. Vertical transmission, mother to child, through placenta or during delivery is frequent, and is of about 50%. First data on heterosexual transmission have been found in Central Africa, indicating high rates for prostitutes, their "customers", unmarried women with numerous partners, women with an other S.T.D. A.I.D.S. in child has been first described in Haïti and in Zaïre. The very important role played by heterosexual transmission imposed sanitary education and usage of contraceptives which are efficient but difficult to firmly recommended for social and cultural considerations.

摘要

逆转录病毒(主要是HIV-1和HIV-2)目前在中非和加勒比群岛广泛传播,尤其是在大城市。它们的传播主要是水平传播,且主要通过性传播。事实上,约80%的病例是由性传播导致的,通过针头(或任何有创材料)、血液或血液制品传播的仅占一小部分。就性传播而言,尽管西方世界最初的疫情爆发使人们将关注点集中在男性同性恋群体上,他们是最早接触艾滋病的人群,但目前已知性传播主要是异性传播,而且是双向的,尽管女性向男性的传播似乎更难解释清楚,因为这在性传播疾病中很常见。向异性伴侣传播病毒的风险在20%至70%之间。在整个月经周期中,精液和宫颈阴道分泌物中都存在病毒。母婴垂直传播,即通过胎盘或分娩过程传播很常见,发生率约为50%。关于异性传播的首批数据是在中非发现的,表明妓女、她们的“顾客”、有多个性伴侣的未婚女性以及患有其他性传播疾病的女性感染率很高。艾滋病在儿童中的情况最早在海地和扎伊尔被描述。异性传播所起的非常重要的作用促使人们开展卫生教育并推广使用避孕药具,避孕药具虽然有效,但由于社会和文化因素很难坚定地推荐使用。

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