Department of Neurosurgery, Rush University, Chicago, Illinois, USA.
Department of Neurosurgery, Rush University, Chicago, Illinois, USA.
World Neurosurg. 2021 Feb;146:e467-e472. doi: 10.1016/j.wneu.2020.10.112. Epub 2020 Oct 29.
OBJECTIVE: Meningiomas of the anterior clinoid process (ACP) present significant surgical challenges given their anatomic relation to critical neurovascular structures. Routine anterior clinoidectomy is often described as a critical step in the resection of these tumors to reduce recurrence and improve visual outcomes. Anterior clinoidectomy, however, is not without risk and its benefits have not been clearly delineated. We present the outcomes of our series of surgically managed ACP meningiomas in which an anterior clinoidectomy was not routinely employed. METHODS: A retrospective review of all ACP meningiomas operated on between August 1997 and March 2019 was conducted. Patients with a recurrent tumor or with <6 months of follow-up were excluded. Resection was typically carried out via a frontotemporal craniotomy followed by intradural removal of the tumor. Anterior clinoidectomy was only performed if hyperostosis of the ACP caused mass effect on the optic nerve. RESULTS: Twenty-nine patients were included in this study. Anterior clinoidectomy was performed in 3 patients (10.3%). Gross total resection was achieved in 22 patients (75.9%). Of the 21 patients (72.4%) who presented with visual deficits, vision improved in 18 patients (85.7%) and worsened in 2 (9.5%). Tumor recurrence occurred in 5 patients (17.2%) at a mean follow-up of 64.9 months. Perioperative morbidity was 10.3%. Permanent morbidity and mortality were 6.9% (vision deterioration) and 0%, respectively. CONCLUSIONS: Resection of ACP meningiomas without routine anterior clinoidectomy minimizes potential risk while achieving gross total resection, recurrence, and visual improvement rates comparable with those in previously reported series.
目的:由于前床突脑膜瘤与关键的神经血管结构的解剖关系,其手术治疗极具挑战性。常规的前床突切除术通常被认为是切除这些肿瘤以降低复发率和改善视力结果的关键步骤。然而,前床突切除术并非没有风险,其益处也尚未明确界定。我们报告了一系列手术治疗的前床突脑膜瘤的结果,其中并未常规采用前床突切除术。
方法:对 1997 年 8 月至 2019 年 3 月间手术治疗的所有前床突脑膜瘤患者进行了回顾性研究。排除复发性肿瘤或随访时间<6 个月的患者。手术切除通常通过额颞开颅术进行,然后在硬脑膜内切除肿瘤。仅在前床突骨质增生对视神经产生压迫效应时才进行前床突切除术。
结果:本研究共纳入 29 例患者。3 例(10.3%)患者接受了前床突切除术。22 例(75.9%)患者实现了大体全切除。21 例(72.4%)存在视力障碍的患者中,18 例(85.7%)视力改善,2 例(9.5%)视力恶化。5 例(17.2%)患者在平均随访 64.9 个月时肿瘤复发。围手术期发病率为 10.3%。永久性发病率和死亡率分别为 6.9%(视力恶化)和 0%。
结论:不常规行前床突切除术切除前床突脑膜瘤可将潜在风险降至最低,同时实现大体全切除率、复发率和视力改善率与先前报道的系列结果相当。
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