Hospital Sao Francisco Xavier, Lisboa, Portugal
Instituto Portugues de Oncologia de Lisboa Francisco Gentil EPE, Lisboa, Portugal.
BMJ Case Rep. 2020 Oct 31;13(10):e238058. doi: 10.1136/bcr-2020-238058.
Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal tumours of the gastrointestinal tract. Oesophageal GISTs are extremely uncommon, accounting for 0.7% of all GISTs, and their management is surrounded by some debate. We report a case of a 70-year-old man who was incidentally diagnosed with an oesophageal lesion on a 18F-fluorodeoxyglucose positron emission tomography. An endoscopic study revealed a non-obstructing 40 mm oesophageal lesion. Endoscopic ultrasound showed a well-circumscribed submucosal tumour on the middle oesophagus. Fine-needle aspiration was positive for CD117 and the overall features were of a GIST. After an initial thoracoscopic approach, the tumour was completely enucleated through a thoracotomy incision. The patient experienced no surgical complications and was discharged on day 4. Histopathology and immunohistochemical staining confirmed a low-risk GIST.
胃肠道间质瘤（GISTs）是胃肠道最常见的间叶性肿瘤。食管 GIST 极为罕见，占所有 GIST 的 0.7%，其治疗存在一些争议。我们报告了一例 70 岁男性病例，他在 18F-氟脱氧葡萄糖正电子发射断层扫描时偶然诊断出食管病变。内镜研究显示食管中段有一个无阻塞的 40mm 食管病变。内镜超声显示中食管有一个边界清楚的黏膜下肿瘤。细针抽吸活检 CD117 阳性，整体表现为 GIST。在初次胸腔镜入路后，通过开胸切口完全进行了肿瘤剜除。患者无手术并发症，并于第 4 天出院。组织病理学和免疫组织化学染色证实为低风险 GIST。
