Sabers Andrew J, Williams Amber L, Farley T Michael
Pharmacy Practice and Science, University of Iowa College of Pharmacy, Iowa City, Iowa, USA.
Pharmacy Practice and Science, University of Iowa College of Pharmacy, Iowa City, Iowa, USA
BMJ Case Rep. 2020 Oct 31;13(10):e239210. doi: 10.1136/bcr-2020-239210.
An 82-year-old man with an extensive medical history presented to the emergency room with complaints of generalised weakness and cough. He tested positive for COVID-19 10 days prior to presenting to the emergency room. Although his symptoms started a week prior to diagnosis, his weakness increased, warranting emergency response. A comprehensive metabolic panel was drawn from the patient on admission, indicating markedly high liver function tests (LFTs) ≥20 times above the upper limit of normal. On day 1 of admission, the decision was still made to start remdesivir (5-day course) due to decompensated acute respiratory failure as well as dexamethasone. The patient's LFTs significantly improved throughout his hospital stay. The patient made a full recovery and was discharged on day 10 of hospitalisation.
一名有广泛病史的82岁男性因全身乏力和咳嗽前往急诊室就诊。他在前往急诊室就诊前10天新冠病毒检测呈阳性。尽管他的症状在诊断前一周就已出现，但乏力症状加重，需要紧急处理。入院时对患者进行了全面代谢检查，结果显示肝功能检查（LFTs）显著升高，比正常上限高出≥20倍。入院第1天，由于急性呼吸衰竭失代偿以及考虑使用地塞米松，仍决定开始使用瑞德西韦（疗程为5天）。患者住院期间肝功能检查结果显著改善。患者完全康复，于住院第10天出院。
