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州医疗事故环境是否会影响脊柱融合术后的结果?对美国 549775 例脊柱融合术后出院患者进行了稳健的统计和机器学习分析。

Does state malpractice environment affect outcomes following spinal fusions? A robust statistical and machine learning analysis of 549,775 discharges following spinal fusion surgery in the United States.

机构信息

1Department of Neurological Surgery, University of California, San Francisco, California.

2Cornell TRIPODS Center for Data Science for Improved Decision-Making and Cornell Tech, Cornell University, New York, New York.

出版信息

Neurosurg Focus. 2020 Nov;49(5):E18. doi: 10.3171/2020.8.FOCUS20610.

DOI:10.3171/2020.8.FOCUS20610
PMID:33130616
Abstract

OBJECTIVE

Spine surgery is especially susceptible to malpractice claims. Critics of the US medical liability system argue that it drives up costs, whereas proponents argue it deters negligence. Here, the authors study the relationship between malpractice claim density and outcomes.

METHODS

The following methods were used: 1) the National Practitioner Data Bank was used to determine the number of malpractice claims per 100 physicians, by state, between 2005 and 2010; 2) the Nationwide Inpatient Sample was queried for spinal fusion patients; and 3) the Area Resource File was queried to determine the density of physicians, by state. States were categorized into 4 quartiles regarding the frequency of malpractice claims per 100 physicians. To evaluate the association between malpractice claims and death, discharge disposition, length of stay (LOS), and total costs, an inverse-probability-weighted regression-adjustment estimator was used. The authors controlled for patient and hospital characteristics. Covariates were used to train machine learning models to predict death, discharge disposition not to home, LOS, and total costs.

RESULTS

Overall, 549,775 discharges following spinal fusions were identified, with 495,640 yielding state-level information about medical malpractice claim frequency per 100 physicians. Of these, 124,425 (25.1%), 132,613 (26.8%), 130,929 (26.4%), and 107,673 (21.7%) were from the lowest, second-lowest, second-highest, and highest quartile states, respectively, for malpractice claims per 100 physicians. Compared to the states with the fewest claims (lowest quartile), surgeries in states with the most claims (highest quartile) showed a statistically significantly higher odds of a nonhome discharge (OR 1.169, 95% CI 1.139-1.200), longer LOS (mean difference 0.304, 95% CI 0.256-0.352), and higher total charges (mean difference [log scale] 0.288, 95% CI 0.281-0.295) with no significant associations for mortality. For the machine learning models-which included medical malpractice claim density as a covariate-the areas under the curve for death and discharge disposition were 0.94 and 0.87, and the R2 values for LOS and total charge were 0.55 and 0.60, respectively.

CONCLUSIONS

Spinal fusion procedures from states with a higher frequency of malpractice claims were associated with an increased odds of nonhome discharge, longer LOS, and higher total charges. This suggests that medicolegal climate may potentially alter practice patterns for a given spine surgeon and may have important implications for medical liability reform. Machine learning models that included medical malpractice claim density as a feature were satisfactory in prediction and may be helpful for patients, surgeons, hospitals, and payers.

摘要

目的

脊柱手术尤其容易引发医疗事故索赔。美国医疗责任制度的批评者认为,该制度推高了成本,而支持者则认为它可以遏制疏忽。在这里,作者研究了医疗事故索赔密度与结果之间的关系。

方法

采用以下方法:1)利用国家执业医师数据库,确定 2005 年至 2010 年期间,每 100 名医生的医疗事故索赔数量,按州划分;2)查询全国住院患者样本,以获取脊柱融合患者;3)查询区域资源文件,以确定各州医生的密度。根据每 100 名医生医疗事故索赔的频率,将各州分为 4 个四分位组。为了评估医疗事故索赔与死亡、出院去向、住院时间(LOS)和总费用之间的关联,使用逆概率加权回归调整估计器。作者控制了患者和医院的特征。使用协变量来训练机器学习模型,以预测死亡、非家庭出院去向、LOS 和总费用。

结果

共确定了 549775 例脊柱融合术后出院患者,其中 495640 例提供了每 100 名医生医疗事故索赔频率的州级信息。其中,124425(25.1%)、132613(26.8%)、130929(26.4%)和 107673(21.7%)分别来自医疗事故索赔每 100 名医生的州的最低、第二低、第二高和最高四分位组。与索赔最少的州(最低四分位组)相比,在索赔最多的州(最高四分位组)进行的手术,非家庭出院的可能性显著更高(OR 1.169,95%CI 1.139-1.200),住院时间更长(平均差异 0.304,95%CI 0.256-0.352),总费用更高(平均差异[对数尺度]0.288,95%CI 0.281-0.295),但死亡率无显著关联。对于包括医疗事故索赔密度作为协变量的机器学习模型,死亡和出院去向的曲线下面积分别为 0.94 和 0.87,LOS 和总费用的 R2 值分别为 0.55 和 0.60。

结论

来自医疗事故索赔频率较高的州的脊柱融合手术与非家庭出院、住院时间延长和总费用增加的可能性增加相关。这表明医疗法律环境可能会改变特定脊柱外科医生的实践模式,并对医疗责任改革具有重要意义。包括医疗事故索赔密度作为特征的机器学习模型在预测方面表现良好,可能对患者、外科医生、医院和支付方都有帮助。

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