Kuge Komei, Matsuda Akihisa, Fujihira Takeaki, Baba Yasuo, Yamada Takeshi, Matsumoto Satoshi, Suzuki Hideyuki, Fujihira Norio, Yoshida Hiroshi
Dept. of Surgery, Kuriyama Central Hospital.
Gan To Kagaku Ryoho. 2020 Sep;47(9):1383-1385.
A 70-year-old male with defecation difficulties was referred to our hospital. A colonoscopy and computed tomography revealed multiple advanced rectal cancers in the rectosigmoid and lower rectum with swollen lymph nodes. After 6 courses of neoadjuvant capecitabine and oxaliplatin and bevacizumab without radiotherapy(CapeOX plus BV therapy), a colonoscopy revealed that the tumors had significantly reduced. A low anterior laparoscopic resection with diverting ileostomy was performed. Histopathological examination showed no residual tumor cells or lymph node metastasis. A final diagnosis of pathological complete response was made. The patient has currently survived 1-year disease-free. Neoadjuvant CapeOX plus BV therapy can be a promising therapeutic option for locally advanced rectal cancer.
