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小儿结直肠外科中实施加速康复外科路径可改善患者结局。

An enhanced recovery after surgery pathway in pediatric colorectal surgery improves patient outcomes.

机构信息

Department of Surgery, University of North Carolina at Chapel Hill, NC.

Department of Pediatrics, University of North Carolina at Chapel Hill, NC.

出版信息

J Pediatr Surg. 2021 Jan;56(1):115-120. doi: 10.1016/j.jpedsurg.2020.09.028. Epub 2020 Oct 6.

Abstract

INTRODUCTION

Enhanced recovery after surgery (ERAS) pathways in adult colorectal surgery are known to reduce complications, readmissions, and length of stay (LOS). However, there is a paucity of ERAS data for pediatric colorectal surgery.

METHODS

A 2014-2018 single-institution, retrospective cohort study was performed on pediatric colorectal surgery patients (2-18 years) pre- and post-ERAS pathway implementation. Bivariate analysis and linear regression were used to determine if ERAS pathway implementation reduced total morphine milligram equivalents per kilogram (MME/kg), LOS, and time to oral intake.

RESULTS

98 (70.5%) and 41 (29.5%) patients were managed with ERAS and non-ERAS pathways, respectively. There was no statistical difference in age, sex, diagnosis, or use of laparoscopic technique between cohorts. The ERAS cohort experienced a significant reduction in total MME/kg, Foley duration, time to oral intake, and LOS with no increase in complications. The presence of an ERAS pathway reduced the total MME/kg (-0.071, 95% CI -0.10, -0.043) when controlling for covariates.

CONCLUSION

The use of an ERAS pathway reduces opioid utilization, which is associated with a reduction in LOS and expedites the initiation of oral intake, in colorectal pediatric surgery patients. Pediatric ERAS pathways should be incorporated into the care of pediatric patients undergoing colorectal surgery.

LEVEL OF EVIDENCE

Level III evidence.

TYPE OF STUDY

Retrospective cohort study.

摘要

简介

成人结直肠手术中的加速康复外科(ERAS)方案已被证实可降低并发症、再入院率和住院时间(LOS)。然而,针对小儿结直肠手术的 ERAS 数据却很少。

方法

对 2014 年至 2018 年接受 ERAS 方案治疗的小儿结直肠手术患者(2-18 岁)进行了单中心回顾性队列研究。采用双变量分析和线性回归来确定 ERAS 方案的实施是否减少了每公斤吗啡毫克当量(MME/kg)、LOS 和口服摄入时间。

结果

98 例(70.5%)和 41 例(29.5%)患者分别接受了 ERAS 和非 ERAS 方案治疗。两组患者在年龄、性别、诊断或腹腔镜技术的使用方面无统计学差异。ERAS 组在不增加并发症的情况下,显著减少了总 MME/kg、导尿管留置时间、口服摄入时间和 LOS。存在 ERAS 方案时,控制了协变量后,总 MME/kg 减少(-0.071,95%CI-0.10,-0.043)。

结论

在小儿结直肠手术患者中,使用 ERAS 方案可减少阿片类药物的使用,从而降低 LOS,并加速口服摄入的开始。小儿 ERAS 方案应纳入小儿患者的治疗中。

证据等级

III 级证据。

研究类型

回顾性队列研究。

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