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增强恢复方案对接受结肠造口关闭和 Malone 手术的儿科患者的影响。

The effect of an enhanced recovery protocol in pediatric patients who undergo colostomy closure and Malone procedures.

机构信息

International Center for Colorectal and Urogenital Care, Division of Pediatric Surgery, Anschutz Medical Campus, Children's Hospital Colorado, 13213 E 16th Ave, Box 323, Aurora, CO, 80045, USA.

Research in Outcomes in Children's Surgery, Children's Hospital Colorado, Aurora, CO, USA.

出版信息

Pediatr Surg Int. 2022 Dec;38(12):1701-1707. doi: 10.1007/s00383-022-05213-z. Epub 2022 Sep 13.

DOI:10.1007/s00383-022-05213-z
PMID:36098796
Abstract

PURPOSE

Pediatric colorectal studies have shown enhanced recovery after surgery (ERAS) protocols can safely improve outcomes. This study sought to determine the impact of an ERAS pathway on the outcomes of children with colorectal conditions who underwent colostomy closure or Malone procedure.

METHODS

A single-institution, retrospective cohort study of children who underwent colostomy closure or Malone procedure between 2016 and 2020 was performed. Differences in outcomes between pre-ERAS and ERAS cohorts were tested. A sub-analysis based on procedure type was performed.

RESULTS

There were 96 patients included: 22 prior to ERAS implementation and 74 after. Patients who underwent ERAS had shorter mean time (hours) to oral intake, mean days until regular diet, post-operative opioid volume, and median length of stay (p < 0.05). There was no difference in complication rates in the ERAS and pre-ERAS cohort (12.2 vs 9.1%, p = 0.99). Patients who underwent colostomy closure after ERAS had lower post-operative opioid use, but no differences were seen in those who underwent Malone.

CONCLUSION

Implementation of an ERAS protocol resulted in quicker time to oral intake, normal diet, and decreased opioid use without increasing complication rates. Differences seen based on procedure type may reflect that the effect of an ERAS protocol is procedure specific.

摘要

目的

儿科结直肠研究表明,加速康复外科(ERAS)方案可以安全地改善治疗结果。本研究旨在确定 ERAS 方案对接受结肠造口还纳或 Malone 手术的结直肠疾病儿童结局的影响。

方法

对 2016 年至 2020 年间接受结肠造口还纳或 Malone 手术的患儿进行单中心回顾性队列研究。比较 ERAS 实施前后两组患儿的结局差异。并基于手术类型进行亚组分析。

结果

共纳入 96 例患儿:ERAS 实施前 22 例,实施后 74 例。ERAS 组患儿的平均进食时间(小时)、恢复正常饮食的天数、术后阿片类药物用量和中位住院时间均较短(p < 0.05)。ERAS 组和 ERAS 前组的并发症发生率无差异(12.2%比 9.1%,p = 0.99)。ERAS 后行结肠造口还纳术的患儿术后阿片类药物用量较低,但 Malone 组患儿无差异。

结论

实施 ERAS 方案可缩短患儿的进食时间、恢复正常饮食和减少阿片类药物的使用,而不会增加并发症的发生率。基于手术类型的差异可能反映 ERAS 方案的效果具有特定的手术针对性。

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本文引用的文献

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J Pediatr Surg. 2022 Jul;57(7):1349-1353. doi: 10.1016/j.jpedsurg.2022.01.004. Epub 2022 Jan 15.
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A Comparison of Adult and Pediatric Enhanced Recovery after Surgery Pathways: A Move for Standardization.
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Implementation and outcomes of enhanced recovery protocols in pediatric surgery: a systematic review and meta-analysis.增强型康复方案在小儿外科学中的实施和结果:系统评价和荟萃分析。
小儿结肠造口关闭术中实施加速康复外科方案:一项随机临床试验。
Pediatr Surg Int. 2025 May 30;41(1):151. doi: 10.1007/s00383-025-06049-z.
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An enhanced recovery after surgery pathway in pediatric colorectal surgery improves patient outcomes.小儿结直肠外科中实施加速康复外科路径可改善患者结局。
J Pediatr Surg. 2021 Jan;56(1):115-120. doi: 10.1016/j.jpedsurg.2020.09.028. Epub 2020 Oct 6.
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Implementation of a pediatric enhanced recovery pathway decreases opioid utilization and shortens time to full feeding.实施儿科强化康复路径可减少阿片类药物的使用并缩短完全喂养时间。
J Pediatr Surg. 2020 Jan;55(1):101-105. doi: 10.1016/j.jpedsurg.2019.09.065. Epub 2019 Nov 15.
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