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一种由天然成分制成的特定滴剂治疗对有皮肤问题的兔子的局部作用:一项初步研究。

Topical effect of a specific spot-on treatment made of natural ingredients in rabbits () with skin problems: A pilot study.

作者信息

Waisburd Galia Sheinberg, Cordero Alberto Martin, Núñez Camilo Romero, Contreras Laura Miranda, Cárdenas Rafael Heredia, Gómez Linda G Bautista

机构信息

Veterinary Center Mexico, Cincinnati Street #22, Benito Juárez, Ciudad de los Deportes, 03710 Mexico city, Mexico.

VETDERM: Specialized Veterinary Dermatology, Guadalajara, Jalisco, Mexico.

出版信息

Vet World. 2020 Sep;13(9):1760-1763. doi: 10.14202/vetworld.2020.1760-1763. Epub 2020 Sep 3.

Abstract

BACKGROUND AND AIM

Rabbits often experience skin diseases. The beneficial effects of plant extracts and essential oils are well known in other species, but the properties of these natural ingredients have not been evaluated in rabbits . The objective of the current study was to evaluate the effect of a topical, commercial solution made of essential oils, plant-extracted polyunsaturated fatty acids, and Vitamin E on rabbits suffering from skin problems.

MATERIALS AND METHODS

Thirty New Zealand rabbits (no sex distinction) were included in this study, with an average weight of 2-3 kg. The rabbits were divided into two groups: The first group was treated with a topical solution made from natural ingredients, and the second was a control group. The rabbits' hair and skin conditions were evaluated on days 1, 14, 28, and 35 after treatment. Data were analyzed using a Kruskal-Wallis range test.

RESULTS

Significant differences were determined in terms of glossy hair variability on days 28 and 35 (p≤0.0001). On days 14-35, hair loss was determined to have reduced (p=0.001), and flaking and odor improved in the treatment group, showing increased scores and significant differences (p=0.0001). By contrast, the control group showed stable overall skin and hair score and an increase in the dryness score.

CONCLUSION

The topical application of essential oils and polyunsaturated fatty acids with Vitamin E was able to improve hair shine and skin hydration and reduce flaking, bad odor, and hair loss, improving the general, and cutaneous aspect of rabbits.

摘要

背景与目的

兔子常患皮肤病。植物提取物和精油在其他物种中的有益作用已广为人知,但这些天然成分的特性尚未在兔子身上进行评估。本研究的目的是评估一种由精油、植物提取的多不饱和脂肪酸和维生素E制成的外用商业溶液对患有皮肤问题的兔子的效果。

材料与方法

本研究纳入30只新西兰兔(无性别区分),平均体重2 - 3千克。兔子被分为两组:第一组用天然成分制成的外用溶液治疗,第二组为对照组。在治疗后第1、14、28和35天评估兔子的毛发和皮肤状况。数据采用Kruskal - Wallis秩和检验进行分析。

结果

在第28天和第35天,有光泽毛发的变化存在显著差异(p≤0.0001)。在第14 - 35天,确定治疗组的脱发减少(p = 0.001),脱屑和异味改善,评分增加且差异显著(p = 0.0001)。相比之下,对照组的皮肤和毛发总体评分稳定,干燥评分增加。

结论

外用精油、多不饱和脂肪酸与维生素E能够改善毛发光泽和皮肤水合作用,减少脱屑、异味和脱发,改善兔子的整体外观和皮肤状况。

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