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内镜超声在儿科患者中的作用:一家三级中心的单中心经验及文献综述。

Role of endoscopic ultrasound in pediatric patients: A single tertiary center experience and review of the literature.

作者信息

Altonbary Ahmed Youssef, Hakim Hazem, Elkashef Wagdi

机构信息

Department of Gastroenterology and Hepatology, Mansoura Specialized Medical Hospital, Mansoura University, Mansoura 35516, Egypt.

Department of Pathology, Mansoura University, Mansoura 35111, Egypt.

出版信息

World J Gastrointest Endosc. 2020 Oct 16;12(10):355-364. doi: 10.4253/wjge.v12.i10.355.

Abstract

BACKGROUND

Although endoscopic ultrasound (EUS) is now widely available and has an established role in adults, the utility of EUS and EUS-guided fine needle aspiration (EUS-FNA) in pediatrics is insufficiently described compared to adults and is supported by only a few studies.

AIM

To report the experience of a single tertiary center in the use of EUS and EUS-FNA in a pediatric population and to further assess its safety, feasibility, and clinical impact on management.

METHODS

A retrospective study of 13 children (aged 18 years or younger) identified from our medical database was conducted. A retrospective review of demographic data, procedure indications, EUS findings, and the clinical impact of EUS on the subsequent management of these patients was performed.

RESULTS

During the 4-year study period, a total of 13 (1.7%) pediatric EUS examinations out of 749 EUS procedures were performed in our unit. The mean age of these 8 females and 5 males was 15.6 years (range: 6-18). Six of the 13 EUS examinations were pancreatobiliary (46.1%), followed by mediastinal 2/13 (15.4%), peri-gastric 2/13 (15.4%), abdominal lymphadenopathy 1/13 (7.7%), tracheal 1/13 (7.7%) and rectal 1/13 (7.7%). Overall, EUS-FNA was performed in 7 patients (53.8%) with a diagnostic yield of 100%. The EUS results had a significant impact on clinical care in 10/13 (77%) cases. No complications occurred in these patients during or after any of the procedures.

CONCLUSION

EUS and EUS-FNA in the pediatric population are safe, feasible, and have a significant clinical impact on the subsequent management; thus avoiding invasive and unnecessary procedures.

摘要

背景

尽管内镜超声(EUS)目前已广泛应用,且在成人中具有明确作用,但与成人相比,EUS及EUS引导下细针穿刺活检(EUS-FNA)在儿科中的应用描述不足,仅有少数研究支持。

目的

报告一家三级中心在儿科人群中使用EUS和EUS-FNA的经验,并进一步评估其安全性、可行性以及对治疗管理的临床影响。

方法

对从我们的医学数据库中识别出的13名18岁及以下儿童进行回顾性研究。对人口统计学数据、操作指征、EUS检查结果以及EUS对这些患者后续治疗管理的临床影响进行回顾性分析。

结果

在4年的研究期间,我们科室共进行了749例EUS检查,其中13例(1.7%)为儿科EUS检查。这8名女性和5名男性的平均年龄为15.6岁(范围:6 - 18岁)。13例EUS检查中,6例为胰胆疾病(46.1%),其次是纵隔疾病2/13(15.4%)、胃周疾病2/13(15.4%)、腹部淋巴结病1/13(7.7%)、气管疾病1/13(7.7%)和直肠疾病1/13(7.7%)。总体而言,7例患者(53.8%)接受了EUS-FNA,诊断阳性率为100%。EUS检查结果对10/13(77%)的病例的临床治疗有显著影响。这些患者在任何操作过程中及操作后均未发生并发症。

结论

儿科人群中的EUS和EUS-FNA是安全、可行的,并且对后续治疗管理有显著的临床影响;从而避免了侵入性和不必要的操作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a922/7579528/6018d65f08df/WJGE-12-355-g001.jpg

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