家族性腺瘤性息肉病：一例病例研究。

Familial adenomatous polyposis: a case study.

作者信息

Yorke Joseph, Yamoah Francis Akwaw, Awoonor-Williams Ronald, Konney Thomas Okpoti, Acheampong Emmanuel, Adjei Ernest, Ababio Kwabena Acheamfour, Aning Daniel Gyawu, Afful-Yorke Dennis, Aidoo Freda Manu, Assim Claudia Gyamfua, Gyamfi Frank Enoch, Assim Raphael Owusu Sekyere, Konadu Saabea Owusu, Kuwornu David Elikplim, Acheampong Emmanuella Nsenbah

机构信息

General Surgery Unit, Directorate of Surgery, Komfo Anokye Teaching Hospital (KATH), Kumasi, Ghana.

Directorate of Obstetrics and Gynaecology, Kumasi, Ghana.

出版信息

J Surg Case Rep. 2020 Oct 27;2020(10):rjaa367. doi: 10.1093/jscr/rjaa367. eCollection 2020 Oct.

DOI:10.1093/jscr/rjaa367

PMID:33133502

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7588306/

Abstract

Familial adenomatous polyposis (FAP) is an inherited syndrome characterized by several adenomatous polyps of the gastrointestinal (GI) mucosa. If treatment is not provided, an average individual with classic FAP will develop colorectal carcinoma around the age of 40 years. The incidence rate of FAP in developing countries like Ghana is unknown compared to advanced countries. We present the first FAP case of a 22-year-old Ghanaian female who presented with massive lower GI bleeding and underwent surgical management after a thorough investigation. The initial assumption that colonic polyps are scarce in native Africans may be more than what is perceived. This highlights the need for the availability of endoscopic services in Ghana.

摘要

家族性腺瘤性息肉病（FAP）是一种遗传性综合征，其特征为胃肠道（GI）黏膜出现多个腺瘤性息肉。如果不进行治疗，典型FAP患者平均会在40岁左右患上结直肠癌。与发达国家相比，在加纳等发展中国家FAP的发病率尚不清楚。我们报告了首例22岁加纳女性FAP病例，该患者出现大量下消化道出血，经过全面检查后接受了手术治疗。最初认为非洲本地人结肠息肉罕见的假设可能比人们所认为的情况更为复杂。这凸显了加纳提供内镜检查服务的必要性。