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一名5个月大的婴儿因食物蛋白诱导的小肠结肠炎综合征对牛奶蛋白过敏而发生心肺骤停。

A 5-Month-Old Infant with Cardiorespiratory Arrest Caused by Food Protein-Induced Enterocolitis Syndrome to Cow's Milk Proteins.

作者信息

Quattromani Martina, Calzedda Roberta, Monti Giovanna

机构信息

Department of Pediatric Allergology, Regina Margherita Children's Hospital, Turin, Italy.

出版信息

J Pediatr Intensive Care. 2020 Dec;9(4):287-289. doi: 10.1055/s-0040-1705184. Epub 2020 Mar 6.

DOI:10.1055/s-0040-1705184
PMID:33133746
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7588293/
Abstract

Food protein-induced enterocolitis syndrome (FPIES) is a nonimmunoglobulin E cell-mediated food allergy, which occurs predominantly in infants and young children. The most commonly incriminated triggers are cow's milk (CM), soy, and grains. Acute FPIES can be potentially life-threatening and culminate in shock requiring fluid resuscitation in at least 15% of the cases. To our knowledge, there have been no reports in literature of cardiorespiratory arrest induced by acute FPIES. We describe the first case of cardiorespiratory arrest occurred after accidental ingestion of a CM-based formula in a 5-month-old infant with previous diagnosis of FPIES to CM.

摘要

食物蛋白诱导的小肠结肠炎综合征(FPIES)是一种非免疫球蛋白E细胞介导的食物过敏,主要发生于婴幼儿。最常见的诱发因素是牛奶(CM)、大豆和谷物。急性FPIES可能会危及生命,至少15%的病例最终会发展为休克,需要进行液体复苏。据我们所知,文献中尚无急性FPIES诱发心肺骤停的报道。我们描述了首例在一名先前诊断为对CM过敏的FPIES的5个月大婴儿意外摄入含CM配方奶粉后发生心肺骤停的病例。

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本文引用的文献

1
International consensus guidelines for the diagnosis and management of food protein-induced enterocolitis syndrome: Executive summary-Workgroup Report of the Adverse Reactions to Foods Committee, American Academy of Allergy, Asthma & Immunology.国际食物蛋白诱导性肠病综合征诊断与管理共识指南:执行摘要-美国过敏、哮喘与免疫学会食物不良反应委员会工作组报告
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Severely Altered-Consciousness Status and Profuse Vomiting in Infants: Food Protein-Induced Enterocolitis Syndrome (FPIES), a Challenging Diagnosis.婴儿严重意识改变状态与大量呕吐:食物蛋白诱导的小肠结肠炎综合征(FPIES),一项具有挑战性的诊断。
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Expression of transforming growth factor beta1, transforming growth factor type I and II receptors, and TNF-alpha in the mucosa of the small intestine in infants with food protein-induced enterocolitis syndrome.食物蛋白诱导的小肠结肠炎综合征婴儿小肠黏膜中转化生长因子β1、转化生长因子I型和II型受体以及肿瘤坏死因子-α的表达
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