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苏醒期谵妄:皮质类固醇会导致这种情况吗?

Emergence Delirium: Can Corticosteroids Contribute to It?

作者信息

Esmel-Vilomara Roger, Cruz Alejandro, Inoriza Cristina, Andreu Eva, Munar Francisca

机构信息

Department of Pediatrics, Hospital Vall d'Hebron, Barcelona, Spain.

Department of Pediatric Nephrology, Hospital Vall d'Hebron, Barcelona, Spain.

出版信息

J Pediatr Intensive Care. 2020 Dec;9(4):304-306. doi: 10.1055/s-0040-1709655. Epub 2020 Apr 17.

DOI:10.1055/s-0040-1709655
PMID:33133750
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7588287/
Abstract

We report a case of emergence delirium after a propofol-based sedation for a renal biopsy in a teenager patient who had received high-dose and long-term corticosteroid treatment. Corticosteroid treatment is proposed as a possible risk factor for emergence delirium, although controlled studies are needed to assess this relationship. Although treatment for emergence delirium has not been well established, as described with steroid-induced psychiatric symptoms, antipsychotics could be a good therapeutic option.

摘要

我们报告了一例青少年患者在接受基于丙泊酚的肾活检镇静后出现谵妄的病例,该患者接受了大剂量和长期的皮质类固醇治疗。尽管需要对照研究来评估这种关系,但皮质类固醇治疗被认为是出现谵妄的一个可能危险因素。虽然针对谵妄的治疗尚未明确,正如类固醇诱导的精神症状所述,抗精神病药物可能是一种很好的治疗选择。

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1
Emergence Delirium: Can Corticosteroids Contribute to It?苏醒期谵妄:皮质类固醇会导致这种情况吗?
J Pediatr Intensive Care. 2020 Dec;9(4):304-306. doi: 10.1055/s-0040-1709655. Epub 2020 Apr 17.
2
3
A comparison of single dose dexmedetomidine with propofol for the prevention of emergence delirium after desflurane anaesthesia in children.右美托咪定与异丙酚单次剂量预防小儿七氟醚麻醉后苏醒期谵妄的比较。
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Feasibility, efficacy, and safety of antipsychotics for intensive care unit delirium: the MIND randomized, placebo-controlled trial.抗精神病药治疗 ICU 谵妄的可行性、疗效和安全性:MIND 随机、安慰剂对照试验。
Crit Care Med. 2010 Feb;38(2):428-37. doi: 10.1097/ccm.0b013e3181c58715.
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Antipsychotics for delirium.用于谵妄的抗精神病药物。
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Efficacy and Tolerability of Atypical Antipsychotics in the Treatment of Delirium: A Systematic Review of the Literature.抗精神病药治疗谵妄的疗效和耐受性:文献系统评价。
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Risperidone in a child with untractable emergency delirium: a case report.利培酮治疗一名儿童难治性急性谵妄:病例报告
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引用本文的文献

1
Delirium in Head Trauma: Looking for a Culprit.颅脑损伤后谵妄:寻找病因。
Rev Recent Clin Trials. 2022;17(4):245-249. doi: 10.2174/1574887117666220811090608.

本文引用的文献

1
Frequency, predictive factors and therapy of emergence delirium: data from a large observational clinical trial in a broad spectrum of postoperative pediatric patients.术后谵妄的发生率、预测因素和治疗:一项广泛观察性临床研究在儿科各类术后患者中的数据。
Minerva Anestesiol. 2019 Jun;85(6):617-624. doi: 10.23736/S0375-9393.19.13038-6. Epub 2019 Jan 18.
2
Steroid-Induced Psychosis in the Pediatric Population: A New Case and Review of the Literature.儿科人群中的类固醇诱导性精神病:一例新病例及文献综述
J Child Adolesc Psychopharmacol. 2018 Jun;28(5):354-359. doi: 10.1089/cap.2018.0017. Epub 2018 Apr 11.
3
Paediatric emergence delirium: a comprehensive review and interpretation of the literature.儿科苏醒期谵妄:文献综述与解读。
Br J Anaesth. 2017 Mar 1;118(3):335-343. doi: 10.1093/bja/aew477.
4
Emergence Delirium in Pediatric Anesthesia.小儿麻醉中的苏醒期谵妄
Paediatr Drugs. 2017 Feb;19(1):11-20. doi: 10.1007/s40272-016-0201-5.
5
Adverse consequences of glucocorticoid medication: psychological, cognitive, and behavioral effects.糖皮质激素药物的不良后果:心理、认知和行为影响。
Am J Psychiatry. 2014 Oct;171(10):1045-51. doi: 10.1176/appi.ajp.2014.13091264.
6
Suicidal behavior and severe neuropsychiatric disorders following glucocorticoid therapy in primary care.糖皮质激素治疗初级保健中自杀行为和严重神经精神障碍。
Am J Psychiatry. 2012 May;169(5):491-7. doi: 10.1176/appi.ajp.2011.11071009.
7
The neuropsychiatric complications of glucocorticoid use: steroid psychosis revisited.糖皮质激素使用的神经精神并发症:类固醇性精神病再探。
Psychosomatics. 2012 Mar-Apr;53(2):103-15. doi: 10.1016/j.psym.2011.12.007.
8
Development and psychometric evaluation of the pediatric anesthesia emergence delirium scale.小儿麻醉苏醒期谵妄量表的编制与心理测量学评估
Anesthesiology. 2004 May;100(5):1138-45. doi: 10.1097/00000542-200405000-00015.