Okuducu Yanki K, Nwosu Adaku, Awad Ahmed, Basak Ratna B
Pediatrics, Brookdale University Hospital Medical Center, New York, USA.
Cureus. 2020 Sep 23;12(9):e10607. doi: 10.7759/cureus.10607.
Fever of unknown origin (FUO) is defined as fever (>101°F) that lasts more than three weeks and for which a cause is not found within seven days of hospital evaluation. FUO has a broad list of differentials - infection, inflammatory diseases, and malignancy. A detailed history and meticulous clinical examination with thorough and stepwise investigations lead to a diagnosis in only two-thirds of cases. In this article, we present a 17-year-old adolescent girl, with no significant past medical history, who presented with FUO during the COVID pandemic. A high index of suspicion and extensive investigations revealed the final diagnosis.
不明原因发热（FUO）的定义为发热（>101°F）持续超过三周，且在医院评估七天内未找到病因。FUO有一系列广泛的鉴别诊断——感染、炎症性疾病和恶性肿瘤。详细的病史、细致的临床检查以及全面且逐步的调查仅能在三分之二的病例中得出诊断。在本文中，我们介绍一名17岁的青少年女性，她既往无重大病史，在新冠疫情期间出现了不明原因发热。高度的怀疑指数和广泛的调查揭示了最终诊断。
