Sano Daisuke, Matsushima Koji, Isono Yasuhiro, Ikui Yukiko, Kinutani Yuri, Chiba Yoshihiro, Hirose Hajime, Oridate Nobuhiko
Department of Otorhinolaryngology Head and Neck Surgery, Yokohama City University, School of Medicine Yokohama Japan.
Department of Otolaryngology Toho University Omori Medical Center Tokyo Japan.
Laryngoscope Investig Otolaryngol. 2020 Sep 30;5(5):895-902. doi: 10.1002/lio2.462. eCollection 2020 Oct.
To evaluate the long-term treatment outcome of type 1 thyroplasty with novel rearrangeable titanium medialization laryngoplasty implant (TMLI) combined with arytenoid adduction (AA) for unilateral vocal cord paralysis (UVFP) in the authors' institution.
A total of 16 Japanese patients with UVFP who received type 1 thyroplasty using TMLI with arytenoid adduction was enrolled in this single-arm, non-randomized interventional study. The results of the auditory perceptual assessment, aerodynamic examination, acoustic measurement, and patient-based survey on these patients were evaluated preoperatively and at 3, 6, and 12 months postoperatively.
Type 1 thyroplasty using TMLI with arytenoid adduction for our patient series presented significant improvements in maximum phonation time, mean flow rates, GRBAS scale, the Voice Handicap Index and the Voice-Related Quality of Life score over the 12-month postoperative period.
Type 1 thyroplasty using TMLI with arytenoid adduction was quite effective for obtaining satisfactory postoperative voice improvement without any surgical complication over the long-term period.
在作者所在机构评估新型可重新排列钛质内移喉成形植入物（TMLI）联合杓状软骨内收术（AA）治疗单侧声带麻痹（UVFP）的1型喉成形术的长期治疗效果。
本单臂、非随机干预性研究纳入了16例接受使用TMLI联合杓状软骨内收术的1型喉成形术的日本UVFP患者。对这些患者术前以及术后3、6和12个月时的听觉感知评估、空气动力学检查、声学测量以及基于患者的调查结果进行了评估。
对于我们的患者系列，使用TMLI联合杓状软骨内收术的1型喉成形术在术后12个月期间，最大发声时间、平均气流量、GRBAS评分、嗓音障碍指数和嗓音相关生活质量评分均有显著改善。
使用TMLI联合杓状软骨内收术的1型喉成形术在长期内对于获得满意的术后嗓音改善且无任何手术并发症相当有效。
