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在社区筛查项目中调整索引/伙伴服务以治疗年轻非裔美国男性衣原体感染

Adapting Index/Partner Services for the Treatment of Chlamydia Among Young African American Men in a Community Screening Program.

作者信息

Jones Austin T, Craig-Kuhn Megan Clare, Schmidt Norine, Gomes Gérard, Scott Glenis, Watson Shannon, Hines Phazal, Davis Javone, Lederer Alyssa M, Martin David H, Kissinger Patricia J

机构信息

From the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine.

Louisiana Office of Public Health, STD/HIV Program.

出版信息

Sex Transm Dis. 2021 May 1;48(5):323-328. doi: 10.1097/OLQ.0000000000001325.

DOI:10.1097/OLQ.0000000000001325
PMID:33137012
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8043978/
Abstract

BACKGROUND

Screening for asymptomatic Chlamydia trachomatis (Ct) among men has not been recommended because feasibility and efficacy are unknown. Check It is a seek-test-treat community-based Ct screening program for African American men who have sex with women and who are 15 to 24 years of age. This is an evaluation of adaptations made to the program aimed at improving index/partner notification and treatment rates.

METHODS

The original Check It intervention included free testing and treatment, contact tracing performed by a third party, expedited index therapy, and expedited partner therapy via pharmacy pickup. The intervention was adapted after a series of in-depth interviews eliciting information to refine the program. Changes included continuity of testing, notification, and treatment by the same staff; expanded hours; and patient-delivered partner therapy with a medication mail-delivery option. Rates of index male and partner treatment were compared using log-binomial models and generalized estimating equations.

RESULTS

Men in the adapted intervention (n = 85) were more likely than men in the original intervention (n = 99) to be contacted (relative risk [RR], 1.14; 95% confidence interval [CI], 1.02-1.27), make a treatment plan (RR, 1.14; 95% CI, 1.01-1.27), and complete treatment (RR, 1.45; 95% CI, 1.20-1.75). Female sexual partners were significantly more likely to complete treatment in postadaptation (n = 153) compared with preadaptation (n = 161; RR, 3.02; 95% CI, 1.81-5.05).

CONCLUSIONS

Compared with third-party notification and expedited index therapy/expedited partner therapy available by pharmacy pickup only, patient-delivered partner therapy with mail-delivery option, staff available at nontraditional hours, and staff continuity across testing, notification, and treatment significantly improved index and partner treatment completion.

摘要

背景

由于可行性和有效性未知,未推荐对男性进行无症状沙眼衣原体(Ct)筛查。“检查项目”是一项针对与女性发生性行为且年龄在15至24岁的非裔美国男性的基于社区的Ct筛查、检测及治疗项目。这是对该项目为提高索引病例/性伴通知率和治疗率所做调整的一项评估。

方法

最初的“检查项目”干预措施包括免费检测和治疗、由第三方进行接触者追踪、加速索引病例治疗以及通过药房取药进行加速性伴治疗。在进行了一系列深入访谈以获取完善该项目的信息后,对干预措施进行了调整。调整内容包括由同一工作人员负责检测、通知和治疗的连续性;延长工作时间;以及提供患者自行送药的性伴治疗及药物邮寄选项。使用对数二项模型和广义估计方程比较索引病例男性和性伴的治疗率。

结果

与原干预措施组(n = 99)的男性相比,调整后干预措施组(n = 85)的男性更有可能被联系到(相对风险[RR],1.14;95%置信区间[CI],1.02 - 1.27)、制定治疗计划(RR,1.14;95% CI,1.01 - 1.27)以及完成治疗(RR,1.45;95% CI,1.20 - 1.75)。与调整前(n = 161)相比,调整后(n = 153)女性性伴完成治疗的可能性显著更高(RR,3.02;95% CI,1.81 - 5.05)。

结论

与仅通过药房取药提供的第三方通知及加速索引病例治疗/加速性伴治疗相比,提供患者自行送药的性伴治疗及药物邮寄选项、非传统工作时间有工作人员以及检测、通知和治疗过程中工作人员的连续性显著提高了索引病例和性伴的治疗完成率。