Departments of Glaucoma.
Paediatric Ophthalmology and Strabismus, Aravind Eye Hospital and Post-Graduate Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India.
J Glaucoma. 2021 May 1;30(5):e271-e273. doi: 10.1097/IJG.0000000000001726.
The aim of the study was to report an infectious cause of congenital pupillary-iris-lens membrane with secondary angle closure glaucoma in an infant.
This was a case report.
Institutional review board exemption for this report was obtained from the Institutional Ethics Committee, Aravind Eye Hospital, Tirunelveli. Informed consent was obtained.A 3-month-old female infant presented to us with congenital pupillary-iris-lens membrane, iris bombe and raised intraocular pressure in the left eye. She underwent trabeculotomy and trabeculectomy along with membranectomy for the same. An aqueous tap performed a month later was suggestive of coexisting Toxoplasma gondii infection detected by polymerase chain reaction.
The study provides a description of the course of management of angle closure glaucoma secondary to congenital pupillary-iris-lens membrane with an associated infection. Intraocular pressure reduced from 40 to 20 mm Hg in the left eye.
This condition is a rare entity of unknown etiology with an increased risk of glaucoma and visual loss. A multidisciplinary approach is needed for the management of these eyes. Infectious associations with these membranes should be ruled out by an aqueous tap with polymerase chain reaction and a close postoperative follow-up is mandatory.
本研究旨在报告一例婴儿先天性瞳孔-虹膜-晶状体膜伴发性闭角型青光眼的感染性病因。
本报告为病例报告。
本研究获得了阿拉文德眼科医院蒂鲁内尔维利机构伦理委员会的机构审查委员会豁免，并获得了知情同意。一名 3 个月大的女性婴儿因左眼先天性瞳孔-虹膜-晶状体膜、虹膜膨隆和眼内压升高而就诊。她接受了小梁切开术和小梁切除术，并同时进行了膜切除术。一个月后进行的房水抽吸提示存在聚合酶链反应检测到的弓形虫感染。
本研究描述了一例先天性瞳孔-虹膜-晶状体膜伴发感染所致闭角型青光眼的治疗过程。左眼眼内压从 40mmHg 降至 20mmHg。
这种情况是一种病因不明的罕见疾病，其青光眼和视力丧失的风险增加。需要多学科方法来管理这些眼睛。应通过房水抽吸和聚合酶链反应排除这些膜的感染性关联，并进行密切的术后随访。
