碳纳米颗粒联合术中神经监测在甲状腺微小乳头状癌手术中的应用。
Application of carbon nanoparticles combined with intraoperative neuromonitoring in papillary thyroid microcarcinoma surgery.
机构信息
Thyroid and Breast Surgery Department, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Thyroid and Breast Surgery Department, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
出版信息
Am J Otolaryngol. 2021 Jan-Feb;42(1):102790. doi: 10.1016/j.amjoto.2020.102790. Epub 2020 Oct 24.
PURPOSES
To improve the lymph node dissection as well as protect parathyroid gland and recurrent laryngeal nerve, the carbon nanoparticles and intraoperative neuromonitoring were applied in papillary thyroid microcarcinoma surgery.
METHODS
Carbon nanoparticles and intraoperative neuromonitoring were used in the experimental group, whereas the control group were not. Routine pathological examination was performed.
RESULTS
The lymph nodes dissected was significantly higher in the experimental group, but the metastatic lymph nodes were not. The number of mistakenly dissected parathyroid gland and postoperative hypoparathyroidism were 3 and 13 in the experimental group respectively, significantly less than 10 and 25 in the control group. The incidences of overall, transient and persistent recurrent laryngeal nerve palsy in the experimental group were 5.5%, 5.5% and 0% respectively, whereas in the control group were 8.6%, 6.9% and 1.7%.
CONCLUSIONS
Carbon nanoparticles can improve lymph node dissection in papillary thyroid microcarcinoma surgery, and the combination of carbon nanoparticles with intraoperative neuromonitoring can reduce surgical complications and improve patient quality of life.
目的
为了提高淋巴结清扫效果，保护甲状旁腺和喉返神经，在甲状腺微小乳头状癌手术中应用了碳纳米颗粒和术中神经监测。
方法
实验组采用碳纳米颗粒和术中神经监测，对照组则不采用。常规进行病理检查。
结果
实验组淋巴结清扫数量明显更高，但转移的淋巴结并无差异。实验组误切甲状旁腺的数量和术后甲状旁腺功能减退的发生率分别为 3 例和 13 例，明显低于对照组的 10 例和 25 例。实验组总、暂时性和永久性喉返神经麻痹的发生率分别为 5.5%、5.5%和 0%，而对照组分别为 8.6%、6.9%和 1.7%。
结论
碳纳米颗粒可提高甲状腺微小乳头状癌手术中的淋巴结清扫效果，而碳纳米颗粒与术中神经监测相结合可以减少手术并发症，提高患者的生活质量。
Zotero 插件