Division of Rhinology and Allergy, Department of Otolaryngology-Head and Neck Surgery, University of Arkansas for Medical Sciences (UAMS), 4301 W Markham St # 543, Little Rock, AR, 72205, USA.
Eur Arch Otorhinolaryngol. 2021 May;278(5):1471-1476. doi: 10.1007/s00405-020-06453-2. Epub 2020 Nov 3.
Chronic rhinosinusitis (CRS) is increasingly common in the elderly population (≥ 65 years old). Compared to their younger counterparts, differences exist in the etiology of CRS and outcomes of Endoscopic Sinus Surgery (ESS) for elderly patients. The aim of this study is to determine if differences in surgical outcomes are present between these two patient populations to facilitate patient pre-operative counseling by their healthcare providers.
Retrospective chart review conducted at a single tertiary care center for patients undergoing ESS between June 2014 and June 2019. Patients were classified into two cohorts (adult and elderly) based on age (< 65 and ≥ 65 years old). Demographics, surgical, and postoperative variables were extracted from our institution's electronic medical records. ANOVA and t-test analysis were performed to determine the presence of significant differences between the two cohorts. SNOT-22 scores were used to determine QOL improvements.
Compared to the adult cohort, elderly patients had significant QOL improvement after surgical treatment (p = 0.001), but had a similar successful response to treatment (p = 0.74). Elderly patients had no difference in the incidence of operative/perioperative complications (p = 0.89) or intraoperative or postoperative bleeding (p = 0.301, p = 0.62), but had an increased incidence of postoperative infection (p = 0.000).
ESS remains an effective treatment modality for the management of CRS, and a safe practice for elderly patients despite the increase in complexity of their medical comorbidities and polypharmacy. QOL improvements are significant, though patient counseling should take into account that improvements may not be as pronounced as in younger patients.
慢性鼻-鼻窦炎(CRS)在老年人群(≥65 岁)中越来越常见。与年轻患者相比,老年患者 CRS 的病因和内镜鼻窦手术(ESS)的治疗效果存在差异。本研究旨在确定这两个患者群体的手术结果是否存在差异,以便为患者提供术前咨询。
对 2014 年 6 月至 2019 年 6 月期间在一家三级医疗中心接受 ESS 的患者进行回顾性图表审查。根据年龄(<65 岁和≥65 岁)将患者分为两个队列(成人和老年)。从我们机构的电子病历中提取人口统计学、手术和术后变量。采用方差分析和 t 检验分析来确定两个队列之间是否存在显著差异。采用 SNOT-22 评分来确定生活质量的改善情况。
与成人组相比,老年患者手术后生活质量有显著改善(p=0.001),但治疗的有效率相似(p=0.74)。老年患者手术/围手术期并发症的发生率无差异(p=0.89),术中或术后出血也无差异(p=0.301,p=0.62),但术后感染的发生率增加(p=0.000)。
尽管老年患者的合并症和药物治疗更加复杂,但 ESS 仍然是治疗 CRS 的有效方法,也是一种安全的治疗方法。生活质量有显著改善,但患者咨询时应考虑到,与年轻患者相比,改善可能不那么明显。