Department of Gynecology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.
Gastrointestinal and Liver Disease Research Center, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.
Int J Gynaecol Obstet. 2021 Feb;152(2):215-219. doi: 10.1002/ijgo.13461. Epub 2020 Dec 2.
To evaluate the clinical presentation of pregnant women in Iran who died due to COVID-19.
Data were evaluated of pregnant women who died following a laboratory diagnosis of COVID-19. The data were obtained from electronic medical records. Additionally, a questionnaire was completed for each patient, including demographic, clinical, laboratorial, imaging, and treatment data. In case of missing information, a member of the research team contacted the first-degree relatives via phone.
Of 32 pregnant women who tested positive for COVID-19, 15 were enrolled into the study (mean age 30.0 ± 5.0 years). The mean time from first symptoms to death was 12 ± 7.0 days. Pre-existing comorbidities were seen in six patients. The main presentations at admission were fatigue and coughing, but most of the women had a fever below 38 °C. Increased white blood cell count and neutrophils were noticeable. A significant drop of saturation of O with ground glass and consolidation seen in both lungs were prominent. The most common complications were acute respiratory distress syndrome followed by respiratory failure.
Computed tomography findings, O pressure, and regular blood assessment may be considered suitable indicators for the surveillance of patients.
评估伊朗因 COVID-19 而死亡的孕妇的临床特征。
评估了经实验室诊断为 COVID-19 后死亡的孕妇的数据。这些数据来自电子病历。此外,为每位患者填写了一份问卷,包括人口统计学、临床、实验室、影像学和治疗数据。对于缺失的信息,研究小组的一名成员通过电话联系了一级亲属。
在 32 名 COVID-19 检测呈阳性的孕妇中,有 15 名被纳入研究(平均年龄 30.0±5.0 岁)。从出现首症到死亡的平均时间为 12±7.0 天。6 名患者存在既往合并症。入院时的主要表现为疲劳和咳嗽,但大多数女性的体温低于 38°C。白细胞计数和中性粒细胞增加明显。双肺磨玻璃影和实变的氧饱和度显著下降。最常见的并发症是急性呼吸窘迫综合征,其次是呼吸衰竭。
CT 检查结果、O 压力和常规血液评估可被视为监测患者的合适指标。