Division of Emergency Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Division of Emergency Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; University of Cincinnati Health System, Cincinnati, Ohio.
J Adolesc Health. 2021 Jan;68(1):57-64. doi: 10.1016/j.jadohealth.2020.09.040. Epub 2020 Nov 2.
Adolescents represent more than half of the newly diagnosed sexually transmitted infections in the U.S. annually. Emergency departments (EDs) may serve as an effective, nontraditional setting to screen for chlamydia/gonorrhea (CT/GC). The objective was to evaluate the effectiveness of a universally offered CT/GC screening program in two pediatric ED settings.
This was a prospective, delayed start pragmatic study conducted over 18 months in two EDs within the same academic institution among ED adolescents aged 14-21 years with any chief complaint. Using a tablet device, adolescents were confidentially informed of CT/GC screening recommendations and were offered screening. If patients agreed to CT/GC testing, a clinical decision support tool was triggered to inform the provider and order testing. The main and key secondary outcomes were the proportion of CT/GC testing and positive CT/GC test results in each respective ED.
Both EDs experienced modest but statistically significant increases in CT/GC testing post- versus pre-intervention (main: 11.5% vs. 7.9%; confidence interval [CI]: 2.9-4.2; p < .0001 and satellite: 3.8% vs. 2.6%; 95% CI: .7-1.7; p < .0001). Among those tested, the positivity rate at the main ED did not significantly change post- versus pre-intervention (24.1% vs. 23.2%; 95% CI: -1.9 to 3.8; p = .71) but significantly decreased at the satellite ED (7.6% vs. 14.8%; 95% CI: -12.2 to -2.2; p = .01).
A universally offered screening intervention increased the proportion of adolescents who were tested at both EDs and the detection rates for CT/GC at the main ED, but patient acceptance of screening was low.
在美国,每年新诊断出的性传播感染病例中,青少年占一半以上。急诊科(ED)可以作为一种有效的、非传统的场所,对衣原体/淋病(CT/GC)进行筛查。目的是评估在同一学术机构内的两个 ED 中,普遍提供 CT/GC 筛查方案的效果。
这是一项在同一学术机构内的两个 ED 中进行的前瞻性、延迟启动的实用研究,对象为年龄在 14-21 岁之间、有任何主诉的 ED 青少年。使用平板电脑,向青少年秘密告知 CT/GC 筛查建议,并提供筛查。如果患者同意 CT/GC 检测,将触发临床决策支持工具,通知提供者并安排检测。主要和关键次要结局是每个 ED 中 CT/GC 检测的比例和 CT/GC 检测阳性结果的比例。
与干预前相比,两个 ED 的 CT/GC 检测率都略有增加,但具有统计学意义(主要:11.5%比 7.9%;置信区间[CI]:2.9-4.2;p<0.0001和卫星:3.8%比 2.6%;95% CI:0.7-1.7;p<0.0001)。在接受检测的人群中,主 ED 的阳性率在干预后与干预前相比没有显著变化(24.1%比 23.2%;95% CI:-1.9 至 3.8;p=0.71),但在卫星 ED 中显著下降(7.6%比 14.8%;95% CI:-12.2 至-2.2;p=0.01)。
普遍提供的筛查干预措施增加了两个 ED 中接受检测的青少年比例,以及主 ED 中 CT/GC 的检出率,但患者对筛查的接受率较低。