Prof. Dr. C. C. Iliescu Emergency Institute for Cardiovascular Diseases, Bucharest, Romania.
Department of Cardio-Thoracic Pathology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
In Vivo. 2020 Nov-Dec;34(6):3681-3685. doi: 10.21873/invivo.12216.
BACKGROUND/AIM: Cardiac papillary fibroelastomas (CPF) are benign tumors, frequently asymptomatic, characterized by a mobile pedunculated mass that arises from the endocardium. When CPF is located in the left ventricle, it may protrude into the left ventricular outflow tract and affect hemodynamics. They are highly thrombogenic, and can also cause some life-threatening events such as cerebral and peripheral embolization.
We herein report a case of a 74-year-old female admitted to our center with palpitations and dyspnea on exertion. Her past medical history revealed that she had had a transient ischemic attack 7 months before presentation. Echocardiography and cardiac magnetic resonance imaging revealed an intracardiac mass anchored in the anteroapical interventricular septum without interference with aortic or mitral valve functionality. Surgical resection of the left ventricular mass was performed through the left apical ventriculotomy approach. Histopathological examination of the tumor was suggestive of papillary fibroelastoma. The postoperative course was uneventful. The patient was discharged home on the eighth postoperative day, with no recurrence at 6 months.
Although left ventricular papillary fibroelastomas are benign tumors, they carry a high risk for embolic complications and therefore surgery should be proposed, the transapical approach being a safe and effective method.
背景/目的:心脏乳头状纤维弹性瘤(CPF)是良性肿瘤,常无症状,其特征是从心内膜长出的可移动的带蒂肿块。当 CPF 位于左心室时,它可能会突入左心室流出道并影响血液动力学。它们具有高度的血栓形成性,还可能导致一些危及生命的事件,如脑和外周栓塞。
我们在此报告一例 74 岁女性因心悸和活动时呼吸困难而入住我院。她的既往病史显示,她在就诊前 7 个月曾发生短暂性脑缺血发作。超声心动图和心脏磁共振成像显示心室内肿块附着在前室间隔的前上,不干扰主动脉瓣或二尖瓣的功能。通过左心尖室切开术进行左心室肿块切除术。肿瘤的组织病理学检查提示为乳头状纤维弹性瘤。术后过程无并发症。患者术后第 8 天出院,6 个月无复发。
尽管左心室乳头状纤维弹性瘤是良性肿瘤,但它们有很高的栓塞并发症风险,因此应建议手术,经心尖途径是一种安全有效的方法。