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一例罕见的同步性多原发性肺癌对吉非替尼有不同反应的病例。

A rare case of synchronous multiple primary lung cancer with different responses to gefitinib.

作者信息

Liao Che-Chi, Lin Yu-Sen, Lin Yu-Chao, Cheng Chiao-Jen, Chen Shuo-Chueh

机构信息

Department of Internal Medicine, China Medical University Hospital, Taichung, 404, Taiwan.

Graduate Institute of Clinical Medical Science, China Medical University, Taichung, 404, Taiwan.

出版信息

Respir Med Case Rep. 2020 Oct 24;31:101270. doi: 10.1016/j.rmcr.2020.101270. eCollection 2020.

DOI:10.1016/j.rmcr.2020.101270
PMID:33145160
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7596341/
Abstract

Differentiating multiple primary lung cancer (MPLC) from lung metastasis is important, and the pathology and gene mutations may be different between the tumors. A lung biopsy to differentiate lesions should be considered, especially when the response of different tumors to treatment is distinct.

摘要

区分多原发性肺癌(MPLC)与肺转移瘤很重要,而且不同肿瘤之间的病理和基因突变可能存在差异。应考虑进行肺活检以鉴别病变,尤其是当不同肿瘤对治疗的反应不同时。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a43/7596341/90ced7f63862/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a43/7596341/91de92a86030/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a43/7596341/90ced7f63862/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a43/7596341/91de92a86030/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a43/7596341/90ced7f63862/gr2.jpg

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本文引用的文献

1
Prognosis of synchronous and metachronous multiple primary lung cancers: systematic review and meta-analysis.同步性和异时性多原发性肺癌的预后:系统评价与荟萃分析
Lung Cancer. 2015 Mar;87(3):303-10. doi: 10.1016/j.lungcan.2014.12.013. Epub 2015 Jan 14.
2
Early clinical diagnosis of synchronous multiple primary lung cancer.同步性多原发性肺癌的早期临床诊断
Oncol Lett. 2012 Jan;3(1):234-237. doi: 10.3892/ol.2011.452. Epub 2011 Oct 19.
3
Multiple lung cancers prognosis: what about histology?多发性肺癌的预后:组织学情况如何?
Ann Thorac Surg. 2008 Sep;86(3):921-6. doi: 10.1016/j.athoracsur.2008.05.041.
4
Synchronous multiple primary lung cancer: an increasing clinical occurrence requiring multidisciplinary management.同步性多原发性肺癌:临床发病率不断上升,需要多学科管理。
J Thorac Cardiovasc Surg. 2007 May;133(5):1193-200. doi: 10.1016/j.jtcvs.2007.01.012.