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在 COVID-19 全球大流行期间对 DXA 检测进行分类的务实建议。

A pragmatic proposal for triaging DXA testing during the COVID-19 global pandemic.

机构信息

The Royal Wolverhampton NHS Trust, Wolverhampton Road, Wolverhampton, WV10 0QP, UK.

Southport and Ormskirk NHS Trust, Southport, PR8 6PN, UK.

出版信息

Osteoporos Int. 2021 Jan;32(1):1-6. doi: 10.1007/s00198-020-05722-4. Epub 2020 Nov 4.

Abstract

The COVID-19 pandemic has resulted in huge disruption to healthcare provision, including to dual-energy X-ray absorptiometry (DXA) imaging. Increased waiting lists for DXA from the pandemic mean potential long and uncertain delays in treatment for osteoporosis. To address these increased waiting lists, we propose a rapid, simple, one-stop algorithm incorporating medication use (aromatase inhibitor, corticosteroid) and clinical risk stratification supplementing a standard FRAX assessment. Our pragmatic algorithm produces a recommendation to treat empirically, image with DXA, or observe. If applied, we model a significant reduction in DXA scan requirements with a corresponding reduction in treatment delays for those awaiting DXA. We estimate this will reduce DXA scan numbers by about 50%, whilst pragmatically ensuring those with the highest clinical need correctly receive treatment without delay. This algorithm will help many clinicians including general practitioners/family physicians prioritise DXA when they may not always have the expertise to make this judgement based on clinical information alone. Although we have used UK guidelines as an example, this approach is flexible enough for adaptation by other countries based on their local guidelines, licensing, prescribing requirements, and DXA waiting list times. There are some limitations to our proposal. However, it represents one way of managing the uncertainty of the current COVID-19 pandemic.

摘要

COVID-19 大流行导致医疗保健服务严重中断,包括双能 X 射线吸收法(DXA)成像。由于大流行,DXA 的等待名单增加,这意味着骨质疏松症的治疗可能会出现长期和不确定的延误。为了解决这些增加的等待名单,我们提出了一种快速、简单、一站式的算法,结合了药物使用(芳香酶抑制剂、皮质类固醇)和临床风险分层,补充了标准 FRAX 评估。我们的实用算法建议根据经验进行治疗、进行 DXA 成像或观察。如果应用,我们预计会减少 DXA 扫描需求,相应地减少等待 DXA 的人的治疗延迟。我们估计这将减少约 50%的 DXA 扫描数量,同时在实践上确保那些具有最高临床需求的人能够及时得到治疗,而不会出现延误。该算法将帮助许多临床医生,包括全科医生/家庭医生,在他们可能不总是仅凭临床信息就有专业知识来做出这一判断时,优先考虑 DXA。尽管我们以英国指南为例,但这种方法足够灵活,可以根据其他国家的当地指南、许可、处方要求和 DXA 等待名单时间进行调整。我们的建议有一些局限性。然而,它代表了一种管理当前 COVID-19 大流行不确定性的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e24/7640538/5a701f8a4b35/198_2020_5722_Fig1_HTML.jpg

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