Connell J, Oozeer R, Regev R, De Vries L S, Dubowitz L M, Dubowitz V
Department of Paediatrics and Neonatal Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, London.
Arch Dis Child. 1987 Oct;62(10):1019-24. doi: 10.1136/adc.62.10.1019.
Continuous monitoring by electroencephalography (EEG) was performed in 31 preterm infants with echodense ultrasound lesions using the Oxford Medilog four channel recorder. In 12 infants these densities preceded cyst formation, eight in the periventricular and four in the subcortical region. In the 19 other infants the densities resolved. The most severe EEG depression occurred in the four infants with subcortical cysts, who also had the poorest outcome. Six of eight infants with periventricular lesions had lesser degrees of abnormality though all infants had moderate to severe handicap at follow up. Similar abnormalities were seen on EEG recording in three infants in whom the densities resolved without cyst formation and these infants also had an abnormal outcome. An abnormal EEG recording provides a sensitive early guide to the severity and prognosis of these lesions, even before they can be seen on ultrasonography.
使用牛津Medilog四通道记录仪对31例患有回声增强超声病变的早产儿进行了脑电图（EEG）连续监测。在12例婴儿中，这些回声增强在囊肿形成之前出现，其中8例在脑室周围，4例在皮质下区域。在其他19例婴儿中，回声增强消失。最严重的脑电图抑制发生在4例患有皮质下囊肿的婴儿中，他们的预后也最差。8例脑室周围病变婴儿中有6例异常程度较轻，尽管所有婴儿在随访时都有中度至重度残疾。在3例回声增强消失且未形成囊肿的婴儿的脑电图记录中也观察到类似异常，这些婴儿也有异常的预后。即使在超声检查中还看不到这些病变，异常的脑电图记录也能为这些病变的严重程度和预后提供敏感的早期指导。
