Harris R L, Musher D M, Bloom K, Gathe J, Rice L, Sugarman B, Williams T W, Young E J
Department of Medicine, Baylor College of Medicine, Houston, TX.
Arch Intern Med. 1987 Nov;147(11):1895-906.
The clinical manifestations of sepsis may be flagrant or subtle. Awareness of the signs and symptoms of sepsis allows early recognition and prompt, appropriate management. The clinical presentation, relative frequency, and current pathophysiologic understanding of the manifestations of sepsis are reviewed. Special emphasis is placed on the cardiopulmonary manifestations, which are examined in a temporal sequence of preshock, early shock, and late shock states. While therapy for the underlying infection (such as antibiotics and drainage of abscesses) is often sufficient, therapy for the specific manifestations of sepsis may also be necessary. Guidelines for therapy for these manifestations of sepsis are given.
脓毒症的临床表现可能很明显，也可能很隐匿。了解脓毒症的体征和症状有助于早期识别并及时进行恰当处理。本文综述了脓毒症临床表现的呈现方式、相对频率以及当前对其病理生理学的认识。重点关注心肺表现，按照休克前期、早期休克和晚期休克状态的时间顺序进行分析。虽然针对潜在感染的治疗（如使用抗生素和引流脓肿）通常就足够了，但针对脓毒症特定表现的治疗可能也有必要。文中给出了针对脓毒症这些表现的治疗指南。
